SCHEMBL952091

SCHEMBL952091

CCOC(=O)CC(=O)c1ccccc1Cl

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERCC5 P28715 1/20 0.56
FEN1 P39748 1/20 0.56
LMNA P02545 2/20 0.54
MEN1 O00255 2/20 0.54
KMT2A Q03164 2/20 0.54
RAB9A P51151 2/20 0.54
KDM4E B2RXH2 1/20 0.54
TSHR P16473 1/20 0.50
NLRP3 Q96P20 1/20 0.50
USP2 O75604 1/20 0.47
CHRM2 P08172 1/20 0.47
CHRM5 P08912 1/20 0.47
CHRM3 P20309 1/20 0.47
HPGD P15428 1/20 0.46
ALDH1A1 P00352 4/20 0.46
NPC1 O15118 1/20 0.46
POLB P06746 1/20 0.46
HTT P42858 1/20 0.46
CES2 O00748 1/20 0.46
CES1 P23141 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31388564 1.00 ERCC5 (0.56) ERCC5FEN1LMNAMEN1KMT2A
SCHEMBL31439626 0.98 ERCC5 (0.54) ERCC5FEN1LMNAMEN1KMT2A
SCHEMBL11163046 0.92 ERCC5 (0.51) ERCC5FEN1LMNAMEN1KMT2A
SCHEMBL12952931 0.87 ERCC5 (0.58) ERCC5FEN1LMNAMEN1KMT2A
SCHEMBL14545873 0.87 ALDH1A1 (0.54) ERCC5FEN1LMNAMEN1KMT2A
SCHEMBL8172213 0.87 ALDH1A1 (0.53) ERCC5FEN1LMNAMEN1KMT2A
SCHEMBL15778916 0.85 TSHR (0.49) ERCC5FEN1LMNAMEN1KMT2A
SCHEMBL3717230 0.84 NLRP3 (0.49) ERCC5FEN1LMNAMEN1KMT2A
SCHEMBL853580 0.84 ERCC5 (0.61) ERCC5FEN1LMNAMEN1KMT2A
SCHEMBL30335736 0.84 ERCC5 (0.61) ERCC5FEN1LMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 335 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12631558-B2 Microfluidic ion detection chip having bubble brightening structure, and detection method thereof SOUTH CHINA UNIVERSITY OF TECHNOLOGY (CN) 2026-05-19 US claimed
CN-119431116-A Method for separating benzenediol isomer and 5-indenol from phenol-containing crude product 煤炭科学技术研究院有限公司 2025-02-14 CN claimed
US-20240125699-A1 MICROFLUIDIC ION DETECTION CHIP HAVING BUBBLE BRIGHTENING STRUCTURE, AND DETECTION METHOD THEREOF SOUTH CHINA UNIVERSITY OF TECHNOLOGY (CN) 2024-04-18 US claimed
CN-117844453-A Grinding fluid manufacturing method 深圳翔合邦泰润滑材料有限公司 2024-04-09 CN claimed
US-11890896-B2 Preparation method of itaconate-butadiene bio-based engineering rubber BEIJING UNIVERSITY OF CHEMICAL TECHNOLOGY (CN) 2024-02-06 US claimed
CN-115976531-A Decontamination cleaning agent, preparation method thereof and aluminum part 中国万宝工程有限公司 2023-04-18 CN claimed
CN-113351375-B Fluorite ore flotation composite collecting agent and preparation method and application thereof 咸阳双佰科技有限责任公司 2023-04-14 CN claimed
CN-113789445-B Method for regenerating ineffective gallium and germanium extractant by organic phase separation 深圳市中金岭南有色金属股份有限公司丹霞冶炼厂 2023-04-07 CN claimed
CN-114920386-B Method for desulfurizing hot spring water and co-producing sulfur soap 四川省银河化学股份有限公司 2023-04-07 CN claimed
CN-115895528-A Single-sided adhesive hydrogel based on unsaturated sodium aliphatate and preparation method and application thereof 华南理工大学 2023-04-04 CN claimed
CN-114568688-A Dietary therapy formula for activating cell regeneration, improving blood circulation and strengthening stem cell fission 盘龙盛 2022-06-03 CN claimed
CN-114557364-A Chlorine dioxide slow-release air freshener 广西环保产业发展研究院有限公司 2022-05-31 CN claimed
CN-114541357-A Contaminated soil separation method for building construction contaminated soil 生态环境部南京环境科学研究所 2022-05-27 CN claimed
CN-112221697-B Novel scheelite rough concentrate heating and reagent removing process 洛阳豫鹭矿业有限责任公司 2022-05-24 CN claimed
CN-109123119-B Additive for improving unsaturated fatty acid content in milk and preparation method thereof 山西农业大学 2022-04-15 CN claimed
CN-114351156-A Dedusting agent and application thereof 广东和胜工业铝材股份有限公司 2022-04-15 CN claimed
CN-114335239-A InP substrate cleaning method 浙江光特科技有限公司 2022-04-12 CN claimed
CN-111167598-B Low-grade lead-zinc oxide ore dressing and smelting treatment method 长沙有色冶金设计研究院有限公司 2022-04-08 CN claimed
CN-114082290-A Method for advanced treatment of secondary steam COD in landfill leachate by MVR evaporation process 中创水务科技环保(广东)有限公司 2022-02-25 CN claimed
CN-113102111-B Oxidized ore flotation agent and preparation method and application thereof 中南大学 2022-02-15 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12631558-B2 Microfluidic ion detection chip having bubble brightening structure, and detection method thereof TMEM63A, SURF4, STUB1 ERCC5 2547/4885FEN1 659/4885LMNA 535/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.