Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NOS2 | P35228 | 1/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8778515 | 0.76 | CES2 (0.46) | ALDH1A1TSHRNOS2CES2CES1 | |
| SCHEMBL1567371 | 0.75 | ALDH1A1 (0.50) | ALDH1A1TSHRAOC3TAAR1SIGMAR1 | |
| SCHEMBL3329127 | 0.75 | CES2 (0.52) | ALDH1A1TSHRCES2CES1AKR1B1 | |
| SCHEMBL28085046 | 0.74 | CES1 (0.55) | ALDH1A1TSHRNOS2CES2CES1 | |
| Hydrochloric Acid SCHEMBL5613814 | 0.73 | CES2 (0.50) | ALDH1A1TSHRCES2CES1AKR1B1 | |
| SCHEMBL7373328 | 0.73 | CES1 (0.48) | ALDH1A1TSHRNOS2TAAR1CES2 | |
| SCHEMBL6318661 | 0.70 | NOS2 (0.52) | ALDH1A1TSHRNOS2TAAR1CES2 | |
| SCHEMBL9055678 | 0.69 | AOC3 (0.42) | ALDH1A1TSHRNOS2AOC3TAAR1 | |
| SCHEMBL5184996 | 0.69 | CES1 (0.55) | ALDH1A1TSHRNOS2CES2CES1 | |
| SCHEMBL8993215 | 0.69 | CES1 (0.55) | ALDH1A1TSHRNOS2CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0390693-B1 | THIOFORMAMIDE DERIVATIVES | RHONE-POULENC SANTE (FR) | 1993-08-25 | — | — | EP | claimed |