Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PREP | P48147 | 1/20 | 0.36 |
| ▸ | TGM2 | P21980 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9258915 | 0.87 | PREP (0.46) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL9263165 | 0.86 | EPHX1 (0.37) | EPHX1DPP8DPP9TDP1ATM | |
| SCHEMBL9263370 | 0.83 | PREP (0.43) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL8438227 | 0.80 | DPP8 (0.42) | EPHX1DPP8DPP9TDP1ATM | |
| SCHEMBL9020075 | 0.79 | NAAA (0.41) | DPP8DPP9TDP1ATMALDH1A1 | |
| SCHEMBL9265506 | 0.78 | PREP (0.47) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL9399827 | 0.78 | ALDH1A1 (0.45) | DPP8DPP9TDP1ATMALDH1A1 | |
| SCHEMBL9362993 | 0.78 | SIGMAR1 (0.43) | EPHX1DPP8DPP9ALDH1A1 | |
| SCHEMBL8436720 | 0.78 | HSD11B1 (0.45) | EPHX1DPP8DPP9TDP1ALDH1A1 | |
| SCHEMBL8441215 | 0.78 | HSD11B1 (0.45) | EPHX1DPP8DPP9TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272455-B1 | 3-Pyrrolidinylthio-1-azabicyclo [3.2.0] hept-2-ene-2-carboxylic acid compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-02-10 | — | — | EP | disclosed |
| US-5138064-A | Chemical intermediate for penicillin derivative | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1992-08-11 | — | — | US | disclosed |
| US-4921852-A | CARBAPENICILLINS | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1990-05-01 | — | — | US | disclosed |
| EP-0272455-A1 | 3-Pyrrolidinylthio-1-azabicyclo [3.2.0] hept-2-ene-2-carboxylic acid compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-06-29 | — | — | EP | disclosed |