SCHEMBL9521247

SCHEMBL9521247

C#CCn1cc(C)sc1=O

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ADORA2B P29275 1/20 0.34
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
KMT2A Q03164 1/20 0.31
AMY1A P0DUB6 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9520398 0.74
SCHEMBL16220653 0.65 ALDH1A1 (0.53) ADORA2BMEN1ALDH1A1MAPTKMT2A
SCHEMBL9519935 0.64
SCHEMBL18118976 0.63
SCHEMBL16975038 0.63 SMN1; SMN2 (0.52) ADORA2BMEN1ALDH1A1KMT2A
SCHEMBL9520707 0.63 CNR2 (0.33) ADORA2BMEN1ALDH1A1KMT2AAMY1A
SCHEMBL9573801 0.61 RAB9A (0.39) ADORA2BMEN1ALDH1A1KMT2A
SCHEMBL28402007 0.61 EP300 (0.37) ADORA2BMEN1ALDH1A1KMT2A
SCHEMBL9520703 0.60 CNR2 (0.32) MEN1ALDH1A1KMT2A
SCHEMBL9409708 0.60 ADORA2B (0.42) ADORA2BKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0300898-B1 PYRETHRINOID DERIVATIVES CONTAINING AN N-HETEROCYCLE, PROCESSES AND INTERMEDIATES FOR THEIR PREPARATION, THEIR USE AS PESTICIDES AND COMPOSITIONS CONTAINING THEM ROUSSEL-UCLAF (FR) 1993-03-10 EP claimed
US-4925862-A PESTICIDES ROUSSEL UCLAF (FR) 1990-05-15 US claimed
US-5008281-A Insecticides, miticides, nematocides ROUSSEL UCLAF (FR) 1991-04-16 US disclosed
US-4925862-A PESTICIDES ROUSSEL UCLAF (FR) 1990-05-15 US disclosed