Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | P2RX7 | Q99572 | 7/20 | 0.48 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9521787 | 0.87 | P2RX7 (0.43) | CNR2KMT2ANPSR1MEN1P2RX7 | |
| SCHEMBL1549023 | 0.73 | P2RX7 (0.73) | CNR2NPSR1P2RX7ALDH1A1MAPT | |
| SCHEMBL9521940 | 0.73 | EPHX2 (0.42) | CNR2KMT2ANPSR1MEN1P2RX7 | |
| SCHEMBL11822463 | 0.73 | P2RX7 (0.74) | CNR2KMT2ANPSR1MEN1P2RX7 | |
| SCHEMBL9124942 | 0.72 | ALDH1A1 (0.59) | KMT2ANPSR1P2RX7ALDH1A1SMN1; SMN2 | |
| SCHEMBL9123251 | 0.72 | GAA (0.62) | KMT2AALDH1A1MAPTGAATDP1 | |
| SCHEMBL993395 | 0.72 | CNR2 (0.63) | CNR2KMT2ANPSR1MEN1P2RX7 | |
| SCHEMBL9127786 | 0.70 | KMT2A (0.49) | KMT2AMEN1ALDH1A1MAPTGAA | |
| SCHEMBL9124861 | 0.70 | KMT2A (0.60) | CNR2KMT2ANPSR1MEN1ALDH1A1 | |
| SCHEMBL14503273 | 0.70 | SMN1; SMN2 (0.66) | CNR2KMT2ANPSR1MEN1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0395093-B1 | TRIPHENYLMETHANE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1993-09-01 | — | — | EP | disclosed |