Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.42 |
| ▸ | CNR2 | P34972 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | STAT6 | P42226 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9521787 | 0.86 | P2RX7 (0.43) | EPHX2CNR2KMT2AMEN1ESR1 | |
| SCHEMBL9521687 | 0.75 | KMT2A (0.48) | KMT2AMEN1KDM4EABCB11LMNA | |
| SCHEMBL9126293 | 0.74 | KDM4E (0.56) | KMT2AMEN1KDM4EABCB11LMNA | |
| SCHEMBL9126492 | 0.74 | KMT2A (0.48) | KMT2AMEN1KDM4EABCB11LMNA | |
| SCHEMBL9521389 | 0.73 | CNR2 (0.57) | CNR2KMT2AMEN1P2RX7NPSR1 | |
| SCHEMBL9126108 | 0.71 | ALDH1A1 (0.57) | KMT2AMEN1KDM4ELMNACYP3A4 | |
| SCHEMBL9122007 | 0.71 | KMT2A (0.65) | KMT2AMEN1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL9122648 | 0.71 | TDP1 (0.50) | KMT2AMEN1KDM4EABCB11LMNA | |
| SCHEMBL9126018 | 0.70 | KMT2A (0.64) | KMT2AMEN1KDM4EABCB11LMNA | |
| SCHEMBL9124818 | 0.70 | TSHR (0.53) | KMT2AMEN1KDM4ELMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0395093-B1 | TRIPHENYLMETHANE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1993-09-01 | — | — | EP | disclosed |