Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 7/20 | 0.43 |
| ▸ | CNR2 | P34972 | 4/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9521389 | 0.87 | CNR2 (0.57) | P2RX7CNR2KMT2AALDH1A1GAA | |
| SCHEMBL9521940 | 0.86 | EPHX2 (0.42) | P2RX7CNR2ADORA1KMT2AALDH1A1 | |
| SCHEMBL9520932 | 0.72 | ALDH1A1 (0.49) | P2RX7CNR2KMT2AALDH1A1GAA | |
| SCHEMBL9124942 | 0.69 | ALDH1A1 (0.59) | P2RX7KMT2AALDH1A1GAATDP1 | |
| SCHEMBL9123251 | 0.69 | GAA (0.62) | KMT2AALDH1A1GAATDP1MAPT | |
| SCHEMBL3685918 | 0.69 | CNR2 (0.49) | P2RX7CNR2ADORA1KMT2AALDH1A1 | |
| SCHEMBL9019625 | 0.69 | KMT2A (0.36) | P2RX7CNR2KMT2AALDH1A1GAA | |
| SCHEMBL9124861 | 0.68 | KMT2A (0.60) | CNR2KMT2AALDH1A1GAATDP1 | |
| SCHEMBL9127786 | 0.68 | KMT2A (0.49) | KMT2AALDH1A1GAATDP1MEN1 | |
| SCHEMBL3805250 | 0.68 | P2RX7 (0.56) | P2RX7CNR2ADORA1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0395093-B1 | TRIPHENYLMETHANE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1993-09-01 | — | — | EP | disclosed |