Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 2/20 | 0.41 |
| ▸ | BACE1 | P56817 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16129686 | 0.82 | CASP6 (0.54) | TSHR | |
| SCHEMBL28135355 | 0.82 | SNCA (0.47) | SNCABACE1EGFRALDH1A1CYP1A2 | |
| SCHEMBL10852408 | 0.81 | ALDH1A1 (0.56) | ALDH1A1KMT2ASMN1; SMN2TDP1TSHR | |
| Di(Hydroxyethyl)Ether SCHEMBL7082245 | 0.80 | TDP1 (0.49) | BACE1ALDH1A1KDM4EALOX15KMT2A | |
| SCHEMBL9383321 | 0.80 | SNCA (0.48) | SNCABACE1EGFRALDH1A1CYP1A2 | |
| SCHEMBL27881156 | 0.79 | SNCA (0.44) | SNCABACE1EGFRALDH1A1CYP1A2 | |
| SCHEMBL5929428 | 0.78 | ALDH1A1 (0.56) | SNCABACE1EGFRALDH1A1CYP1A2 | |
| SCHEMBL9281293 | 0.76 | PDK1 (0.55) | SNCABACE1EGFRALDH1A1CYP1A2 | |
| SCHEMBL28760029 | 0.75 | SNCA (0.47) | SNCABACE1EGFRALDH1A1CYP1A2 | |
| SCHEMBL9445071 | 0.74 | TSHR (0.47) | ALDH1A1KDM4EALOX15KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0359618-B1 | 2-SUBSTITUTED PARA-AMINOPHENOLS AND THEIR USE IN THE COLORATION OF KERATINIC FIBRES | L'OREAL (FR) | 1993-03-17 | — | — | EP | disclosed |
| EP-0359618-A1 | 2-Substituted para-aminophenols and their use in the coloration of keratinic fibres | L'OREAL (FR) | 1990-03-21 | — | — | EP | disclosed |