Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HCAR3 | P49019 | 13/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL177446 | 0.88 | HCAR3 (0.53) | CASP6TSHRLMNAHCAR3 | |
| SCHEMBL17511817 | 0.86 | HCAR3 (0.58) | CASP6TSHRLMNAHCAR3 | |
| SCHEMBL28545324 | 0.85 | CASP6 (0.50) | CASP6TSHRLMNAHCAR3APEX1 | |
| SCHEMBL28748754 | 0.84 | HCAR3 (0.51) | CASP6TSHRLMNAHCAR3 | |
| SCHEMBL16129649 | 0.84 | HCAR3 (0.56) | CASP6TSHRLMNAHCAR3 | |
| SCHEMBL9521545 | 0.82 | SNCA (0.41) | TSHR | |
| SCHEMBL8092214 | 0.82 | CASP6 (0.64) | CASP6TSHRLMNAHCAR3APEX1 | |
| SCHEMBL4175596 | 0.81 | CASP6 (0.58) | CASP6TSHRLMNAHCAR3APEX1 | |
| SCHEMBL30481076 | 0.81 | CASP6 (0.66) | CASP6TSHRLMNAHCAR3APEX1 | |
| SCHEMBL1483517 | 0.81 | CASP6 (0.66) | CASP6TSHRLMNAHCAR3APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014147182-A2 | NOVEL COMPOUNDS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2014-09-25 | — | — | WO | disclosed |