SCHEMBL9521180

SCHEMBL9521180

C=CCn1c(C(F)(F)F)c(CO)sc1=O

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.37
SHMT2 P34897 1/20 0.32
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10392131 0.79 CYP3A4 (0.41) CYP3A4SHMT2
SCHEMBL10392132 0.78 CYP3A4 (0.39) CYP3A4SHMT2POLB
SCHEMBL9521586 0.77 CYP3A4 (0.36) CYP3A4SHMT2POLB
SCHEMBL9866650 0.74 POLB (0.52) POLB
SCHEMBL9867430 0.72
SCHEMBL9521058 0.72 KDM4E (0.47)
SCHEMBL9521710 0.62 CYP3A4 (0.41) CYP3A4
SCHEMBL9867861 0.61 ALDH1A1 (0.36)
SCHEMBL5068338 0.61 CYP3A4 (0.59) CYP3A4
SCHEMBL4622249 0.60 CYP3A4 (0.46) CYP3A4POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0300898-B1 PYRETHRINOID DERIVATIVES CONTAINING AN N-HETEROCYCLE, PROCESSES AND INTERMEDIATES FOR THEIR PREPARATION, THEIR USE AS PESTICIDES AND COMPOSITIONS CONTAINING THEM ROUSSEL-UCLAF (FR) 1993-03-10 EP disclosed
US-5008281-A Insecticides, miticides, nematocides ROUSSEL UCLAF (FR) 1991-04-16 US disclosed
US-4925862-A PESTICIDES ROUSSEL UCLAF (FR) 1990-05-15 US disclosed