Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9521586 | 0.81 | CYP3A4 (0.36) | POLBALDH1A1LMNAHSD17B10SMN1; SMN2 | |
| SCHEMBL9867238 | 0.80 | HDAC3 (0.38) | POLBALDH1A1HPGDKMT2AMAPT | |
| SCHEMBL9868262 | 0.79 | CNR2 (0.48) | ALDH1A1KMT2AMAPTHSD17B10MEN1 | |
| SCHEMBL10392132 | 0.76 | CYP3A4 (0.39) | POLBALDH1A1HPGDLMNAKMT2A | |
| SCHEMBL9521180 | 0.74 | CYP3A4 (0.37) | POLB | |
| SCHEMBL10392131 | 0.71 | CYP3A4 (0.41) | — | |
| SCHEMBL4218274 | 0.67 | KDM4E (0.46) | POLBALDH1A1HPGDLMNAKMT2A | |
| SCHEMBL23479896 | 0.66 | POLB (0.48) | POLBALDH1A1HPGDLMNAKMT2A | |
| SCHEMBL8320324 | 0.64 | ALDH1A1 (0.48) | POLBALDH1A1HPGDLMNAKMT2A | |
| SCHEMBL11392334 | 0.64 | ALDH1A1 (0.54) | POLBALDH1A1HPGDLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5008281-A | Insecticides, miticides, nematocides | ROUSSEL UCLAF (FR) | 1991-04-16 | — | — | US | disclosed |
| US-4925862-A | PESTICIDES | ROUSSEL UCLAF (FR) | 1990-05-15 | — | — | US | disclosed |