Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 7/20 | 0.46 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | STAT6 | P42226 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9521940 | 0.75 | EPHX2 (0.42) | KMT2AP2RX7MEN1KDM4EABCB11 | |
| SCHEMBL9122648 | 0.74 | TDP1 (0.50) | KMT2AMEN1KDM4EABCB11LMNA | |
| SCHEMBL9126293 | 0.70 | KDM4E (0.56) | KMT2AMEN1KDM4EABCB11LMNA | |
| SCHEMBL9126492 | 0.70 | KMT2A (0.48) | KMT2AMEN1KDM4EABCB11LMNA | |
| SCHEMBL9122007 | 0.67 | KMT2A (0.65) | KMT2AMEN1NPC1 | |
| SCHEMBL4207053 | 0.67 | P2RX7 (0.85) | KMT2AP2RX7MEN1 | |
| SCHEMBL9126018 | 0.66 | KMT2A (0.64) | KMT2AMEN1NPC1KDM4EABCB11 | |
| SCHEMBL9126538 | 0.66 | MAPT (0.52) | KMT2AMEN1NPC1KDM4EABCB11 | |
| SCHEMBL9125034 | 0.66 | EGFR (0.51) | KMT2AMEN1NPC1 | |
| SCHEMBL9124818 | 0.66 | TSHR (0.53) | KMT2AMEN1NPC1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0395093-B1 | TRIPHENYLMETHANE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1993-09-01 | — | — | EP | disclosed |