Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10392131 | 0.66 | CYP3A4 (0.41) | CYP3A4NPSR1 | |
| SCHEMBL10392132 | 0.64 | CYP3A4 (0.39) | CYP3A4LMNANPSR1 | |
| SCHEMBL5068338 | 0.64 | CYP3A4 (0.59) | CYP3A4NPSR1 | |
| SCHEMBL9521180 | 0.62 | CYP3A4 (0.37) | CYP3A4 | |
| SCHEMBL16047233 | 0.62 | CYP3A4 (0.62) | CYP3A4LMNANPSR1 | |
| SCHEMBL9521586 | 0.61 | CYP3A4 (0.36) | CYP3A4LMNA | |
| SCHEMBL28662 | 0.60 | CYP3A4 (1.00) | CYP3A4NPSR1 | |
| SCHEMBL6566578 | 0.58 | LMNA (0.51) | CYP3A4LMNA | |
| SCHEMBL10997976 | 0.57 | CYP3A4 (0.79) | CYP3A4LMNANPSR1 | |
| SCHEMBL13278595 | 0.57 | CYP3A4 (0.54) | CYP3A4LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0300898-B1 | PYRETHRINOID DERIVATIVES CONTAINING AN N-HETEROCYCLE, PROCESSES AND INTERMEDIATES FOR THEIR PREPARATION, THEIR USE AS PESTICIDES AND COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1993-03-10 | — | — | EP | disclosed |
| EP-0300898-A1 | Pyrethrinoid derivatives containing an N-heterocycle, processes and intermediates for their preparation, their use as pesticides and compositions containing them | ROUSSEL-UCLAF (FR) | 1989-01-25 | — | — | EP | disclosed |