SCHEMBL9521795

SCHEMBL9521795

O=C1NC(Nc2ccccc2)OC1=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DDB1 Q16531 1/20 0.40
CRBN Q96SW2 1/20 0.40
GSK3B P49841 3/20 0.39
NFKB1 P19838 2/20 0.39
NFKB2 Q00653 1/20 0.39
RELA Q04206 1/20 0.39
ALDH1A1 P00352 6/20 0.36
TDP1 Q9NUW8 3/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
NPSR1 Q6W5P4 2/20 0.36
KDM4E B2RXH2 2/20 0.36
MAPT P10636 2/20 0.36
HPGD P15428 2/20 0.36
MEN1 O00255 1/20 0.36
RGS12 O14924 1/20 0.36
GMNN O75496 1/20 0.36
PRKD3 O94806 1/20 0.36
EGFR P00533 1/20 0.36
LMNA P02545 1/20 0.36
PRKCG P05129 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7672741 0.70 MEN1 (0.50) ALDH1A1KDM4EHPGDMEN1KMT2A
SCHEMBL5472792 0.65 NFKB1 (0.42) DDB1CRBNNFKB1NFKB2RELA
SCHEMBL8315872 0.64 TNKS2 (0.34) KDM4EHPGDMEN1LMNAMAPK1
SCHEMBL7532940 0.63 DDB1 (0.40) DDB1CRBNGSK3BNFKB1NFKB2
SCHEMBL11845041 0.63 KDM4E (0.60) GSK3BALDH1A1SMN1; SMN2KDM4EMAPT
SCHEMBL11243841 0.63 DDB1 (0.44) DDB1CRBNNFKB1NFKB2RELA
SCHEMBL9843841 0.63 NFKB1 (0.36) DDB1CRBNNFKB1NFKB2RELA
SCHEMBL27527981 0.62 ALDH1A1 (0.43) DDB1CRBNNFKB1NFKB2RELA
SCHEMBL8975934 0.62 ALDH1A1 (0.38) NFKB1NFKB2RELAALDH1A1TDP1
SCHEMBL15509478 0.61 NFKB1 (0.42) DDB1CRBNNFKB1NFKB2RELA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1028143-C Oxazolidinone sterilization composition DU PONT (US) 1995-04-12 CN claimed
CN-1096157-A Antifungal De oxazolidone DU PONT (US) 1994-12-14 CN claimed
CN-1047079-A FUNGICIDAL OXAZOLIDINONES DU PONT (US) 1990-11-21 CN claimed
CN-1028143-C Oxazolidinone sterilization composition DU PONT (US) 1995-04-12 CN disclosed
CN-1096157-A Antifungal De oxazolidone DU PONT (US) 1994-12-14 CN disclosed
EP-0533734-A1 FUNGICIDAL IMINOOXAZOLIDINONES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-03-31 EP disclosed
CN-1047079-A FUNGICIDAL OXAZOLIDINONES DU PONT (US) 1990-11-21 CN disclosed