SCHEMBL7672741

SCHEMBL7672741

O=C1NC(c2ccccc2)OC1=O

nearest known ligand 0.62

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
POLB P06746 1/20 0.50
CA2 P00918 1/20 0.44
KDM4E B2RXH2 6/20 0.43
HSD17B10 Q99714 4/20 0.43
ALDH1A1 P00352 4/20 0.43
USP2 O75604 1/20 0.43
GAA P10253 1/20 0.43
TNKS2 Q9H2K2 1/20 0.42
HPGD P15428 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5624732 0.81 MEN1 (0.77) MEN1KMT2APOLBKDM4EHSD17B10
SCHEMBL18324078 0.77 TNKS2 (0.52) MEN1KMT2APOLBCA2KDM4E
SCHEMBL8958512 0.72 SIRT1 (0.44) MEN1KMT2APOLBCA2KDM4E
SCHEMBL15669988 0.70 SMN1; SMN2 (0.54) MEN1KMT2ACA2KDM4EHSD17B10
SCHEMBL11156568 0.70 CA2 (0.41) MEN1KMT2APOLBCA2KDM4E
SCHEMBL30209785 0.70 MEN1 (0.49) MEN1KMT2APOLBKDM4EHSD17B10
SCHEMBL9521795 0.70 DDB1 (0.40) MEN1KMT2APOLBCA2KDM4E
SCHEMBL541947 0.70 MEN1 (0.49) MEN1KMT2APOLBKDM4EHSD17B10
SCHEMBL10834102 0.70 CA2 (0.46) MEN1KMT2APOLBCA2KDM4E
SCHEMBL13633794 0.70 ALDH1A1 (0.38) MEN1KMT2APOLBCA2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6444613-B1 EFFECTING LEAF ABSCISSION IN PLANTS BY TREATING PLANTS WITH SYNERGISTIC MIXTURE COMPRISING THIDIAZURON OR THIDIAZURON AND DIURON AND ONE OR MORE PROTOPORPHYRINOGEN OXIDASE INHIBITORS HOECHST SCHERING AGREVO GMBH (DE) 2002-09-03 US disclosed