Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | PCNA | P12004 | 4/20 | 0.34 |
| ▸ | MIF | P14174 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CKS1B | P61024 | 1/20 | 0.32 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9522476 | 0.86 | PCNA (0.37) | PCNAMIFALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL9522866 | 0.75 | PCNA (0.36) | PCNAMIFALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL1133432 | 0.71 | PCNA (0.36) | PCNAALDH1A1CYP1A2CYP3A4ALOX15 | |
| SCHEMBL874767 | 0.71 | PCNA (0.36) | PCNAALDH1A1CYP1A2CYP3A4ALOX15 | |
| SCHEMBL22468340 | 0.70 | PCNA (0.35) | PCNAALDH1A1CYP1A2CYP3A4ALOX15 | |
| SCHEMBL4954960 | 0.69 | MTNR1A (0.35) | ESR2PCNA | |
| SCHEMBL9522068 | 0.65 | ESR1 (0.58) | ESR1ESR2MIF | |
| SCHEMBL9522073 | 0.65 | ESR1 (0.58) | ESR1ESR2MIF | |
| Hydrochloric Acid SCHEMBL10531318 | 0.64 | MEN1 (0.48) | PCNAALDH1A1HPGDALOX12HIF1A | |
| Hydrochloric Acid SCHEMBL9522600 | 0.64 | ESR1 (0.56) | ESR1ESR2MIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5273885-A | Using a polyiodothyronine analog of a phenyl compound containing a hydroxyl group ortho to an iodine | SYNTEX (U.S.A.) INC. (US) | 1993-12-28 | — | — | US | disclosed |