Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCNA | P12004 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | THRB | P10828 | 3/20 | 0.33 |
| ▸ | TTR | P02766 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.33 |
| ▸ | THRA | P10827 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9522866 | 0.89 | PCNA (0.36) | PCNAMEN1KMT2ALMNATHRB | |
| SCHEMBL9522015 | 0.86 | ESR1 (0.35) | PCNAHSD17B10CYP1A2CYP2C9ALDH1A1 | |
| SCHEMBL1133432 | 0.83 | PCNA (0.36) | PCNAMEN1KMT2ALMNAADORA3 | |
| SCHEMBL874767 | 0.83 | PCNA (0.36) | PCNAMEN1KMT2ALMNAADORA3 | |
| SCHEMBL22468340 | 0.81 | PCNA (0.35) | PCNAMEN1KMT2ALMNAADORA3 | |
| SCHEMBL4954960 | 0.80 | MTNR1A (0.35) | PCNASLC7A5 | |
| SCHEMBL1572564 | 0.70 | KDM4E (0.56) | PCNAMEN1KMT2ALMNATHRB | |
| SCHEMBL1572565 | 0.70 | KDM4E (0.56) | PCNAMEN1KMT2ALMNATHRB | |
| SCHEMBL31189933 | 0.70 | KDM4E (0.56) | PCNAMEN1KMT2ALMNATHRB | |
| SCHEMBL4566314 | 0.68 | SLC7A5 (0.53) | SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5273885-A | Using a polyiodothyronine analog of a phenyl compound containing a hydroxyl group ortho to an iodine | SYNTEX (U.S.A.) INC. (US) | 1993-12-28 | — | — | US | disclosed |