Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCNA | P12004 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1133432 | 1.00 | PCNA (0.36) | PCNAKMT2ACYP3A4KDM4EALDH1A1 | |
| SCHEMBL22468340 | 0.98 | PCNA (0.35) | PCNAKMT2ACYP3A4KDM4EALDH1A1 | |
| SCHEMBL9522866 | 0.85 | PCNA (0.36) | PCNAKMT2ACYP3A4KDM4EALDH1A1 | |
| SCHEMBL9522476 | 0.83 | PCNA (0.37) | PCNAKMT2ACYP3A4ALDH1A1LMNA | |
| SCHEMBL4954960 | 0.79 | MTNR1A (0.35) | PCNASLC7A5 | |
| SCHEMBL11356756 | 0.77 | KDM6B (0.33) | KMT2ACYP3A4KDM4EALDH1A1LMNA | |
| SCHEMBL31189933 | 0.77 | KDM4E (0.56) | PCNAKMT2ACYP3A4KDM4EALDH1A1 | |
| SCHEMBL1572564 | 0.77 | KDM4E (0.56) | PCNAKMT2ACYP3A4KDM4EALDH1A1 | |
| SCHEMBL1572565 | 0.77 | KDM4E (0.56) | PCNAKMT2ACYP3A4KDM4EALDH1A1 | |
| SCHEMBL169322 | 0.76 | SLC7A5 (0.55) | SLC7A5CAMK2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120077268-A1 | ANIMAL-FREE CELL CULTURE METHOD | GLAXOSMITHKLINE BIOLOGICALS, S.A. (BE) | 2012-03-29 | — | — | US | claimed |
| US-20120077268-A1 | ANIMAL-FREE CELL CULTURE METHOD | GLAXOSMITHKLINE BIOLOGICALS, S.A. (BE) | 2012-03-29 | — | — | US | disclosed |
| US-8034617-B2 | Cell culture in culture media free of components of animal origin | GLAXOSMITHKLINE BIOLOGICALS S.A. (BE) | 2011-10-11 | — | — | US | disclosed |
| EP-2192175-A1 | Animal-free cell culture method | GlaxoSmithKline Biologicals S.A. (BE) | 2010-06-02 | — | — | EP | disclosed |
| EP-2186885-A1 | Animal-free cell culture method | GlaxoSmithKline Biologicals S.A. (BE) | 2010-05-19 | — | — | EP | disclosed |
| US-20060183224-A1 | Animal-free cell culture method | GLAXOSMITHKLINE BIOLOGICALS, S.A. (BE) | 2006-08-17 | — | — | US | disclosed |
| EP-1599580-A1 | ANIMAL-FREE CELL CULTURE METHOD | GlaxoSmithKline Biologicals S.A. (BE) | 2005-11-30 | — | — | EP | disclosed |
| WO-2004078955-A1 | ANIMAL-FREE CELL CULTURE METHOD | GLAXOSMITHKLINE BIOLOGICALS S.A. (BE) | 2004-09-16 | — | — | WO | disclosed |