Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.34 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | PCNA | P12004 | 1/20 | 0.32 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26122075 | 0.82 | CTSS (0.44) | ITGA4ITGB7SLC7A5CTSSCTSK | |
| SCHEMBL26122077 | 0.82 | CTSS (0.44) | ITGA4ITGB7SLC7A5CTSSCTSK | |
| SCHEMBL29641584 | 0.82 | CTSS (0.44) | ITGA4ITGB7SLC7A5CTSSCTSK | |
| SCHEMBL9522866 | 0.82 | PCNA (0.36) | PCNASLC7A5 | |
| SCHEMBL9522476 | 0.80 | PCNA (0.37) | PCNASLC7A5 | |
| SCHEMBL29286182 | 0.79 | MTNR1A (0.33) | MTNR1AMTNR1BITGA4ITGB7SLC7A5 | |
| SCHEMBL29286181 | 0.79 | MTNR1A (0.33) | MTNR1AMTNR1BITGA4ITGB7SLC7A5 | |
| SCHEMBL1133432 | 0.79 | PCNA (0.36) | PCNASLC7A5 | |
| SCHEMBL874767 | 0.79 | PCNA (0.36) | PCNASLC7A5 | |
| SCHEMBL22468340 | 0.77 | PCNA (0.35) | PCNASLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080318842-A1 | Cyclic Isodityrosine Derivatives | KEIO UNIVERSITY (JP) | 2008-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080318842-A1 | Cyclic Isodityrosine Derivatives | NR1H4, OAT, CYP3A5 | MTNR1A 2674/4885MTNR1B 2163/4885EGFR 1639/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.