Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | FNTA | P49354 | 1/20 | 0.47 |
| ▸ | FNTB | P49356 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP4 | P49662 | 1/20 | 0.41 |
| ▸ | CASP5 | P51878 | 1/20 | 0.41 |
| ▸ | RGS12 | O14924 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28944685 | 0.86 | NFKB1 (0.54) | NFKB1KCNH2NFKB2RELAFNTA | |
| SCHEMBL9069884 | 0.84 | NFKB1 (0.58) | NFKB1KCNH2NFKB2RELAFNTA | |
| SCHEMBL10944464 | 0.83 | NFKB1 (0.55) | NFKB1KCNH2NFKB2RELAFNTA | |
| SCHEMBL11332229 | 0.83 | CYP19A1 (0.57) | CYP19A1CYP17A1 | |
| SCHEMBL22038641 | 0.82 | FNTA (0.51) | NFKB1KCNH2NFKB2RELAFNTA | |
| SCHEMBL8752386 | 0.80 | FNTA (0.61) | NFKB1KCNH2NFKB2RELAFNTA | |
| SCHEMBL21243060 | 0.80 | FNTA (0.61) | NFKB1KCNH2NFKB2RELAFNTA | |
| SCHEMBL2120270 | 0.80 | FNTA (0.61) | NFKB1KCNH2NFKB2RELAFNTA | |
| SCHEMBL17992570 | 0.80 | FNTA (0.61) | NFKB1KCNH2NFKB2RELAFNTA | |
| Acetic Acid SCHEMBL2582613 | 0.80 | FNTA (0.60) | NFKB1KCNH2NFKB2RELAFNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4116314-A1 | METHOD FOR PREPARING 16ALPHA-HYDROXYPREDNISOLONE | Zhejiang Shenzhou Pharmaceutical Company Limited (CN) | 2023-01-11 | — | — | EP | claimed |
| CN-108912194-B | A kind of preparation method of 21-hydroxy-1,4,9(11),16-pregnatetraene-3,20-dione-21-acetate | 奥锐特药业股份有限公司 | 2019-11-19 | — | — | CN | claimed |
| CN-108912194-A | A kind of preparation method of 21-hydroxy-1,4,9(11),16-pregnatetraene-3,20-dione-21-acetate | 奥锐特药业股份有限公司 | 2018-11-30 | — | — | CN | claimed |
| CN-107814824-A | A kind of preparation method of 21-hydroxy-1,4,9(11),16-pregnatetraene-3,20-dione-21-acetate | 浙江仙琚制药股份有限公司 | 2018-03-20 | — | — | CN | claimed |
| CN-105622699-A | Method for preparing tetraene acetate and derivatives thereof | HUNAN CHENGDA BIOTECHNOLOGY CO LTD | 2016-06-01 | — | — | CN | claimed |
| CN-105543319-A | Method for preparing steroidanti-inflammatory drugintermediatetetraene acetate using enzyme process | ENZYMEWORKS INC | 2016-05-04 | — | — | CN | claimed |
| EP-0308412-B1 | 16$g(a)-METHYLATION PROCESS | THE UPJOHN COMPANY (US) | 1992-03-18 | — | — | EP | claimed |
| US-11618766-B2 | Method for preparing 16Alpha-hydroxyprednisolone | ZHEJIANG SHENZHOU PHARMACEUTICAL COMPANY LIMITED (CN) | 2023-04-04 | — | — | US | disclosed |
| US-11618766-B2 | Method for preparing 16Alpha-hydroxyprednisolone | ZHEJIANG SHENZHOU PHARMACEUTICAL COMPANY LIMITED (CN) | 2023-04-04 | — | — | US | disclosed |
| US-20230028248-A1 | METHOD FOR PREPARING 16ALPHA-HYDROXYPREDNISOLONE | ZHEJIANG SHENZHOU PHARMACEUTICAL COMPANY LIMITED (CN) | 2023-01-26 | — | — | US | disclosed |
| US-20230028248-A1 | METHOD FOR PREPARING 16ALPHA-HYDROXYPREDNISOLONE | ZHEJIANG SHENZHOU PHARMACEUTICAL COMPANY LIMITED (CN) | 2023-01-26 | — | — | US | disclosed |
| EP-4116314-A1 | METHOD FOR PREPARING 16ALPHA-HYDROXYPREDNISOLONE | Zhejiang Shenzhou Pharmaceutical Company Limited (CN) | 2023-01-11 | — | — | EP | disclosed |
| EP-4116314-A1 | METHOD FOR PREPARING 16ALPHA-HYDROXYPREDNISOLONE | Zhejiang Shenzhou Pharmaceutical Company Limited (CN) | 2023-01-11 | — | — | EP | disclosed |
| CN-106905406-A | A kind of preparation technology of Triamcinolone acetonide | 河南利华制药有限公司 | 2017-06-30 | — | — | CN | disclosed |
| CN-105622699-A | Method for preparing tetraene acetate and derivatives thereof | HUNAN CHENGDA BIOTECHNOLOGY CO LTD | 2016-06-01 | — | — | CN | disclosed |
| CN-105543319-A | Method for preparing steroidanti-inflammatory drugintermediatetetraene acetate using enzyme process | ENZYMEWORKS INC | 2016-05-04 | — | — | CN | disclosed |
| CN-102863505-B | Process for synthesizing triamcinolone acetonide acetate | BAOJI KANGLE BIOTECHNOLOGY CO LTD | 2015-03-04 | — | — | CN | disclosed |
| CN-104231031-A | Preparation method of triamcinolone acetonide | JIANGXI GANLIANG MEDICINE RAW MATERIAL CO LTD | 2014-12-24 | — | — | CN | disclosed |
| CN-102863505-A | Process for synthesizing triamcinolone acetonide acetate | BAOJI KANGLE BIOTECHNOLOGY CO LTD | 2013-01-09 | — | — | CN | disclosed |
| CN-101633682-A | Refining technique of intermediate acetate arachidonic substance of triamcinolone acetonide series products | YANAN ZHU | 2010-01-27 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230028248-A1 | METHOD FOR PREPARING 16ALPHA-HYDROXYPREDNISOLONE | HSD17B2, HSD11B1, CYP17A1 | NFKB1 733/4885KCNH2 4657/4885NFKB2 1109/4885 |
| US-11618766-B2 | Method for preparing 16Alpha-hydroxyprednisolone | HSD17B2, HSD11B1, CYP17A1 | NFKB1 733/4885KCNH2 4657/4885NFKB2 1109/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.