SCHEMBL94876

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL23319728	0.84	ALDH1A1 (0.38)	TSHRALDH1A1GLATAAR1GRIN1
	SCHEMBL2545305	0.83	TSHR (0.41)	TSHRALDH1A1GLATAAR1GRIN1
	SCHEMBL94693	0.81	TAAR1 (0.46)	TSHRALDH1A1GLATAAR1LMNA
	SCHEMBL3956329	0.80	TAAR1 (0.39)	TSHRALDH1A1GLATAAR1GRIN1
	SCHEMBL25684761	0.80	TAAR1 (0.39)	TSHRALDH1A1GLATAAR1GRIN1
	SCHEMBL95222	0.79	SIGMAR1 (0.36)	TSHRALDH1A1GLATAAR1SIGMAR1
	SCHEMBL17045962	0.78	TAAR1 (0.38)	TSHRALDH1A1GLATAAR1GRIN1
	SCHEMBL10690755	0.78	TSHR (0.50)	TSHRALDH1A1TAAR1LMNATP53
	SCHEMBL95074	0.77	TSHR (0.42)	TSHRALDH1A1GLAGRIN1GRIN2A
	SCHEMBL95073	0.75	TSHR (0.41)	TSHRALDH1A1GLATAAR1GRIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.