Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | GLP1R | P43220 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 2/20 | 0.31 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11735926 | 0.82 | CCNB2 (0.38) | KDM4EGAAPDE4A | |
| SCHEMBL11735541 | 0.82 | SLC29A1 (0.35) | KDM4EGAAPDE4A | |
| SCHEMBL9520382 | 0.78 | LMNA (0.39) | KDM4EGAALMNAPOLBHTT | |
| SCHEMBL12235624 | 0.78 | KDM4E (0.41) | KDM4EGAALMNASMN1; SMN2PDE4A | |
| SCHEMBL9519918 | 0.77 | LMNA (0.34) | LMNASMN1; SMN2POLBHTT | |
| SCHEMBL11735611 | 0.77 | CTSS (0.40) | KDM4EGAA | |
| SCHEMBL11092336 | 0.74 | PGK1 (0.45) | KDM4EGAALMNA | |
| SCHEMBL17008720 | 0.73 | HTT (0.41) | KDM4EGAALMNAHTT | |
| SCHEMBL29693655 | 0.71 | KDM4E (0.48) | KDM4EGAASMN1; SMN2POLB | |
| SCHEMBL2383543 | 0.71 | KDM4E (0.48) | KDM4EGAASMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4054655-A | FUNGICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-10-18 | — | — | US | claimed |
| EP-0308895-B1 | DICYANOPYRAZINE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND FUNGICIDE | HODOGAYA CHEMICAL CO., LTD. (JP) | 1993-06-16 | — | — | EP | disclosed |
| US-5093335-A | Agricultural and horticultural | HODOGAYA CHEMICAL COMPANY, LTD. (JP) | 1992-03-03 | — | — | US | disclosed |
| EP-0308895-A1 | Dicyanopyrazine compounds, process for their preparation and fungicide | HODOGAYA CHEMICAL CO., LTD. (JP) | 1989-03-29 | — | — | EP | disclosed |
| US-4054655-A | FUNGICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-10-18 | — | — | US | disclosed |
| US-4054655-A | FUNGICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-10-18 | — | — | US | disclosed |