Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | BCL9 | O00512 | 1/20 | 0.45 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.42 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.42 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8435360 | 0.90 | RAB9A (0.48) | ALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL10670147 | 0.85 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2HTR2ABCL9CTNNB1 | |
| SCHEMBL8510870 | 0.84 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2LMNARAB9ANPC1 | |
| SCHEMBL8510873 | 0.84 | RAB9A (0.50) | ALDH1A1SMN1; SMN2RAB9ANPC1MEN1 | |
| SCHEMBL8717644 | 0.84 | ALDH1A1 (0.50) | ALDH1A1LMNARAB9ANPC1MEN1 | |
| SCHEMBL8432142 | 0.84 | RAB9A (0.46) | ALDH1A1RAB9ANPC1 | |
| SCHEMBL11270421 | 0.82 | RAB9A (0.48) | ALDH1A1SMN1; SMN2RAB9ANPC1MEN1 | |
| SCHEMBL29280745 | 0.80 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2RAB9ANPC1MEN1 | |
| SCHEMBL3336144 | 0.78 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2LMNAHTTGAA | |
| SCHEMBL9667101 | 0.78 | SMN1; SMN2 (0.54) | ALDH1A1SMN1; SMN2HTR2ALMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0354583-B1 | DC-88A derivatives | KYOWA HAKKO KOGYO KK (JP) | 1993-11-03 | — | — | EP | disclosed |
| US-5117006-A | DC-88A DERIVATIVES USEFUL AS ANTITUMOR AGENTS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-05-26 | — | — | US | disclosed |
| US-5084468-A | Antitumor agents | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-01-28 | — | — | US | disclosed |
| EP-0354583-A1 | DC-88A derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1990-02-14 | — | — | EP | disclosed |