Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8435360 | 0.94 | RAB9A (0.48) | RAB9AALDH1A1NPC1TDP1ATM | |
| SCHEMBL8717644 | 0.89 | ALDH1A1 (0.50) | RAB9AALDH1A1NPC1TDP1ATM | |
| SCHEMBL8510870 | 0.87 | ALDH1A1 (0.49) | RAB9AALDH1A1NPC1TDP1ATM | |
| SCHEMBL8510873 | 0.84 | RAB9A (0.50) | RAB9AALDH1A1NPC1TDP1ATM | |
| SCHEMBL9522656 | 0.84 | ALDH1A1 (0.53) | RAB9AALDH1A1NPC1 | |
| SCHEMBL11270421 | 0.82 | RAB9A (0.48) | RAB9AALDH1A1NPC1TDP1ATM | |
| SCHEMBL29280745 | 0.82 | ALDH1A1 (0.62) | RAB9AALDH1A1NPC1TDP1ATM | |
| SCHEMBL11274033 | 0.79 | LMNA (0.47) | ALDH1A1TDP1MAPT | |
| SCHEMBL1270807 | 0.79 | LMNA (0.51) | ALDH1A1TDP1MAPT | |
| SCHEMBL28480949 | 0.78 | ALDH1A1 (0.50) | RAB9AALDH1A1NPC1ATMCRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5885816-A | OPTICALLY RESOLVING A RACEMIC MIXTURE OF AMINO ACID DERIVATIVES, COMPRISING USING A NONSPECIFIC CATALYTIC ANTIBODY WHICH ENANTIOSELECTIVELY HYDROLIZES VARIOUS AMINO ACID ESTER DERIVATIVES | PROTEIN ENGINEERING RESEARCH INSTITUTE (JP) | 1999-03-23 | — | — | US | disclosed |
| EP-0765940-A1 | CATALYTIC ANTIBODY WHICH HYDROLYZES AMINO ACID ESTER DERIVATIVE ENANTIOSELECTIVELY | PROTEIN ENGINEERING RESEARCH INSTITUTE (JP) | 1997-04-02 | — | — | EP | disclosed |