Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | APLNR | P35414 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.38 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9521967 | 0.85 | MAPT (0.41) | KMT2AMEN1RXFP1RAB9ANPC1 | |
| SCHEMBL9522162 | 0.83 | RAB9A (0.43) | KMT2AMEN1RAB9ANPC1MITF | |
| SCHEMBL9523127 | 0.83 | ALDH1A1 (0.38) | KMT2AMEN1RXFP1RAB9ANPC1 | |
| SCHEMBL9776505 | 0.81 | ALDH1A1 (0.40) | KMT2AMEN1RXFP1RAB9AALDH1A1 | |
| SCHEMBL10372931 | 0.80 | KDM4E (0.50) | KMT2AMEN1RAB9ANPC1ALDH1A1 | |
| SCHEMBL9521955 | 0.79 | LOX (0.38) | KMT2AMEN1RXFP1RAB9ANPC1 | |
| SCHEMBL9776524 | 0.77 | TXNRD1 (0.44) | KMT2AMEN1RXFP1RAB9AALDH1A1 | |
| SCHEMBL9532673 | 0.76 | SOAT1 (0.44) | KMT2AMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL9533205 | 0.76 | SOAT1 (0.44) | KMT2AMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL9523984 | 0.76 | PKM (0.62) | RAB9ANPC1ALDH1A1MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0242690-B1 | 5H-1,3,4-Thiadiazolo[3,2-a]pyrimidin-5-one derivatives and agricultural-horticultural fungicide composition containing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1993-06-30 | — | — | EP | claimed |
| EP-0242690-A2 | 5H-1,3,4-Thiadiazolo[3,2-a]pyrimidin-5-one derivatives and agricultural-horticultural fungicide composition containing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1987-10-28 | — | — | EP | claimed |
| JP-63045286-A | — | — | None | — | — | JP | disclosed |
| EP-0242690-B1 | 5H-1,3,4-Thiadiazolo[3,2-a]pyrimidin-5-one derivatives and agricultural-horticultural fungicide composition containing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1993-06-30 | — | — | EP | disclosed |
| US-4985432-A | 5H-1,3,4-thiadiazolo(3,2-A)pyrimidin-5-one derivatives and agricultural-horticultural fungicide composition containing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1991-01-15 | — | — | US | disclosed |
| JP-S6345286-A | 5H-1,3,4-THIADIAZOLO(3,2-A)PYRIMIDIN-5-ONE DERIVATIVE AND AGRICULTURAL AND HORTZCULTURAL GERMICIDE CONTAINING SAID COMPOUND AS ACTIVE INGREDIENT | KUMIAI CHEM IND CO LTD | 1988-02-26 | — | — | JP | disclosed |
| EP-0242690-A2 | 5H-1,3,4-Thiadiazolo[3,2-a]pyrimidin-5-one derivatives and agricultural-horticultural fungicide composition containing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1987-10-28 | — | — | EP | disclosed |