Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 16/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9523113 | 0.86 | MEN1 (0.43) | P2RX7MEN1KMT2ARXFP1F2RL3 | |
| SCHEMBL9522166 | 0.86 | KMT2A (0.43) | P2RX7MEN1KMT2ARXFP1F2RL3 | |
| SCHEMBL9523131 | 0.83 | MEN1 (0.43) | P2RX7MEN1KMT2ARXFP1F2RL3 | |
| SCHEMBL10372932 | 0.81 | P2RX7 (0.46) | P2RX7MEN1KMT2A | |
| SCHEMBL9776511 | 0.81 | ALDH1A1 (0.41) | P2RX7MEN1KMT2ARXFP1F2RL3 | |
| SCHEMBL9523990 | 0.77 | POLB (0.49) | P2RX7MEN1KMT2AF2RL3 | |
| SCHEMBL9532679 | 0.77 | SOAT1 (0.40) | MEN1KMT2AF2RL3 | |
| SCHEMBL9522502 | 0.77 | MEN1 (0.40) | MEN1KMT2ARXFP1 | |
| SCHEMBL9522767 | 0.75 | KMT2A (0.42) | P2RX7MEN1KMT2ARXFP1 | |
| SCHEMBL9776526 | 0.73 | TXNRD1 (0.43) | P2RX7MEN1KMT2ARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0242690-B1 | 5H-1,3,4-Thiadiazolo[3,2-a]pyrimidin-5-one derivatives and agricultural-horticultural fungicide composition containing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1993-06-30 | — | — | EP | claimed |
| EP-0242690-A2 | 5H-1,3,4-Thiadiazolo[3,2-a]pyrimidin-5-one derivatives and agricultural-horticultural fungicide composition containing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1987-10-28 | — | — | EP | claimed |
| JP-63045286-A | — | — | None | — | — | JP | disclosed |
| EP-0242690-B1 | 5H-1,3,4-Thiadiazolo[3,2-a]pyrimidin-5-one derivatives and agricultural-horticultural fungicide composition containing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1993-06-30 | — | — | EP | disclosed |
| US-4985432-A | 5H-1,3,4-thiadiazolo(3,2-A)pyrimidin-5-one derivatives and agricultural-horticultural fungicide composition containing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1991-01-15 | — | — | US | disclosed |
| JP-S6345286-A | 5H-1,3,4-THIADIAZOLO(3,2-A)PYRIMIDIN-5-ONE DERIVATIVE AND AGRICULTURAL AND HORTZCULTURAL GERMICIDE CONTAINING SAID COMPOUND AS ACTIVE INGREDIENT | KUMIAI CHEM IND CO LTD | 1988-02-26 | — | — | JP | disclosed |
| EP-0242690-A2 | 5H-1,3,4-Thiadiazolo[3,2-a]pyrimidin-5-one derivatives and agricultural-horticultural fungicide composition containing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1987-10-28 | — | — | EP | disclosed |