Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 13/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 2/20 | 0.36 |
| ▸ | PARG | Q86W56 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9524203 | 0.82 | POLB (0.36) | MAPTNPSR1USP30GAANSD2 | |
| SCHEMBL9021100 | 0.81 | USP30 (0.32) | MAPTNPSR1USP30 | |
| SCHEMBL9523787 | 0.81 | CA1 (0.41) | — | |
| SCHEMBL9217889 | 0.81 | USP30 (0.37) | USP30NSD2ALOX5APFEN1 | |
| SCHEMBL9020663 | 0.80 | ALDH1A1 (0.35) | MAPTNPSR1USP30 | |
| SCHEMBL9524222 | 0.79 | NSD2 (0.39) | MAPTUSP30GAANSD2PARG | |
| SCHEMBL10688726 | 0.75 | NSD2 (0.38) | MAPTUSP30GAANSD2PARG | |
| SCHEMBL8615855 | 0.74 | NSD2 (0.36) | MAPTNPSR1USP30NSD2PARG | |
| SCHEMBL8111692 | 0.74 | NSD2 (0.36) | MAPTNPSR1USP30NSD2PARG | |
| SCHEMBL7806538 | 0.71 | USP30 (0.34) | USP30NSD2ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0575378-A1 | BENZENESULFONYLUREA DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1993-12-29 | — | — | EP | disclosed |