SCHEMBL8615855

SCHEMBL8615855

CC(=O)OC(CF)c1ccccc1S(=O)(=O)NC(C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
NSD2 O96028 2/20 0.36
PARG Q86W56 1/20 0.35
USP30 Q70CQ3 8/20 0.35
ALOX5AP P20292 6/20 0.34
FEN1 P39748 6/20 0.34
MAPT P10636 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8618669 0.81 CA1 (0.41)
SCHEMBL9217880 0.81 USP30 (0.35) NSD2USP30ALOX5APFEN1
SCHEMBL8111692 0.80 NSD2 (0.36) NSD2PARGUSP30ALOX5APFEN1
SCHEMBL8637572 0.79 KDM4E (0.32) USP30MAPTNPSR1
SCHEMBL8636612 0.78 LMNA (0.35) USP30MAPTNPSR1
SCHEMBL9523006 0.74 MAPT (0.37) NSD2PARGUSP30ALOX5APFEN1
SCHEMBL8615221 0.73 GAA (0.52) MAPT
SCHEMBL14328457 0.71 NSD2 (0.47) NSD2PARGALOX5APFEN1MAPT
SCHEMBL8615033 0.71 CA9 (0.44) NSD2PARGUSP30ALOX5APFEN1
SCHEMBL9259502 0.70 USP30 (0.35) USP30

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5736628-A HERBICIDE KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1998-04-07 US disclosed
US-5461025-A Herbicides KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1995-10-24 US disclosed
EP-0575378-A1 BENZENESULFONYLUREA DERIVATIVES KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1993-12-29 EP disclosed
WO-1992015568-A1 BENZENESULFONYLUREA DERIVATIVES KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1992-09-17 WO disclosed