Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 11/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NSD2 | O96028 | 2/20 | 0.35 |
| ▸ | PARG | Q86W56 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9021083 | 0.84 | CA12 (0.31) | CA12CA1CA2ADRB2ADRB1 | |
| SCHEMBL9523006 | 0.82 | MAPT (0.37) | MAPTNPSR1USP30GAANSD2 | |
| SCHEMBL9524222 | 0.82 | NSD2 (0.39) | MAPTUSP30GAANSD2PARG | |
| SCHEMBL10688726 | 0.78 | NSD2 (0.38) | POLBMAPTUSP30GAANSD2 | |
| SCHEMBL9700175 | 0.68 | NSD2 (0.44) | POLBMAPTUSP30GAANSD2 | |
| SCHEMBL9021012 | 0.68 | CA2 (0.34) | CA12CA1CA2CA9 | |
| SCHEMBL9657049 | 0.68 | CA12 (0.42) | MAPTGAANSD2CA12CA1 | |
| SCHEMBL8615855 | 0.68 | NSD2 (0.36) | MAPTNPSR1USP30NSD2PARG | |
| SCHEMBL8111692 | 0.68 | NSD2 (0.36) | MAPTNPSR1USP30NSD2PARG | |
| SCHEMBL9217889 | 0.67 | USP30 (0.37) | POLBUSP30NSD2ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0575378-A1 | BENZENESULFONYLUREA DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1993-12-29 | — | — | EP | disclosed |