Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.58 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.56 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | ATM | Q13315 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7294999 | 0.89 | SMN1; SMN2 (0.54) | SMN1; SMN2TP53THRBKCNK9KCNK3 | |
| SCHEMBL7296065 | 0.85 | PKM (0.57) | SMN1; SMN2TP53THRBKCNK9KCNK3 | |
| SCHEMBL9525322 | 0.85 | NPC1 (0.59) | TP53S1PR4NPC1RAB9AKDM4E | |
| SCHEMBL15149513 | 0.85 | SMN1; SMN2 (0.50) | SMN1; SMN2TP53THRBKCNK9KCNK3 | |
| SCHEMBL2351309 | 0.85 | ALDH1A1 (0.56) | SMN1; SMN2TP53THRBNPC1RAB9A | |
| SCHEMBL7295972 | 0.84 | RAB9A (0.69) | SMN1; SMN2TP53THRBKCNK9KCNK3 | |
| SCHEMBL9523014 | 0.84 | S1PR4 (0.69) | SMN1; SMN2S1PR4HDAC1HDAC6NPC1 | |
| SCHEMBL28605755 | 0.83 | POLB (0.54) | SMN1; SMN2TP53THRBKCNK9KCNK3 | |
| SCHEMBL7294803 | 0.83 | KCNK9 (0.58) | SMN1; SMN2TP53THRBKCNK9KCNK3 | |
| SCHEMBL9522743 | 0.82 | S1PR4 (0.58) | TP53S1PR4NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358118-B1 | Phenylamides - process for their preparation as well as a drug containing those compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1994-03-16 | — | — | EP | disclosed |
| US-5135949-A | Anticoagulants | BOEHRINGER MANNHEIM GMBH (DE) | 1992-08-04 | — | — | US | disclosed |
| EP-0358118-A1 | Phenylamides - process for their preparation as well as a drug containing those compounds | Roche Diagnostics GmbH (DE) | 1990-03-14 | — | — | EP | disclosed |