Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9523291 | 0.91 | KDM4E (0.51) | ALDH1A1KDM4EHSD17B10HPGDLMNA | |
| SCHEMBL9523609 | 0.89 | ALDH1A1 (0.47) | ALDH1A1KDM4EHSD17B10HPGDMAPT | |
| SCHEMBL9523449 | 0.89 | ALDH1A1 (0.39) | ALDH1A1KDM4EHSD17B10HPGDMAPT | |
| SCHEMBL9522474 | 0.88 | KDM4E (0.50) | ALDH1A1KDM4EHSD17B10HPGDHTT | |
| SCHEMBL9522013 | 0.86 | ALDH1A1 (0.55) | ALDH1A1KDM4EHSD17B10HPGDMAPT | |
| SCHEMBL9523430 | 0.84 | KDM4E (0.44) | ALDH1A1KDM4EHSD17B10HPGDMAPT | |
| SCHEMBL9521886 | 0.82 | KDM4E (0.44) | ALDH1A1KDM4EHSD17B10HPGDHTT | |
| SCHEMBL10744715 | 0.80 | ALDH1A1 (0.44) | ALDH1A1KDM4EHSD17B10HPGDMAPT | |
| SCHEMBL10770586 | 0.77 | ALDH1A1 (0.40) | ALDH1A1KDM4EHSD17B10HPGDMAPT | |
| SCHEMBL9522977 | 0.76 | ALDH1A1 (0.54) | ALDH1A1KDM4EHSD17B10HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0249043-B1 | QUINOLINECARBOXYLIC ACID DERIVATIVES | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-08-04 | — | — | EP | disclosed |
| US-4843070-A | BACTERIDCIDES, FUNGICIDES | NIPPON SHINYAKU CO., LTD. (JP) | 1989-06-27 | — | — | US | disclosed |
| EP-0249043-A2 | Quinolinecarboxylic acid derivatives | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1987-12-16 | — | — | EP | disclosed |