Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | IDE | P14735 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9523083 | 0.89 | ALDH1A1 (0.49) | ALDH1A1KDM4EHSD17B10HPGDTSHR | |
| SCHEMBL9522257 | 0.84 | LMNA (0.44) | ALDH1A1KDM4EHSD17B10HPGDTSHR | |
| SCHEMBL9523291 | 0.79 | KDM4E (0.51) | ALDH1A1KDM4EHSD17B10HPGDMEN1 | |
| SCHEMBL10744715 | 0.78 | ALDH1A1 (0.44) | ALDH1A1KDM4EHSD17B10HPGDTSHR | |
| SCHEMBL9523609 | 0.78 | ALDH1A1 (0.47) | ALDH1A1KDM4EHSD17B10HPGDMAPT | |
| SCHEMBL9522474 | 0.77 | KDM4E (0.50) | ALDH1A1KDM4EHSD17B10HPGDTSHR | |
| SCHEMBL9525764 | 0.76 | ALDH1A1 (0.40) | ALDH1A1KDM4EHPGDMAPTMEN1 | |
| SCHEMBL10982068 | 0.76 | ALDH1A1 (0.46) | ALDH1A1KDM4EHSD17B10HPGDTSHR | |
| SCHEMBL9522013 | 0.75 | ALDH1A1 (0.55) | ALDH1A1KDM4EHSD17B10HPGDTSHR | |
| SCHEMBL9523430 | 0.73 | KDM4E (0.44) | ALDH1A1KDM4EHSD17B10HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0249043-B1 | QUINOLINECARBOXYLIC ACID DERIVATIVES | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-08-04 | — | — | EP | disclosed |
| US-4843070-A | BACTERIDCIDES, FUNGICIDES | NIPPON SHINYAKU CO., LTD. (JP) | 1989-06-27 | — | — | US | disclosed |
| EP-0249043-A2 | Quinolinecarboxylic acid derivatives | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1987-12-16 | — | — | EP | disclosed |