Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | RAD52 | P43351 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9523083 | 0.91 | ALDH1A1 (0.49) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL9522474 | 0.90 | KDM4E (0.50) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL9523609 | 0.89 | ALDH1A1 (0.47) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL9523430 | 0.87 | KDM4E (0.44) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL9522977 | 0.86 | ALDH1A1 (0.54) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL10770586 | 0.86 | ALDH1A1 (0.40) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL9521886 | 0.84 | KDM4E (0.44) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL9522285 | 0.83 | LMNA (0.57) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL9675363 | 0.83 | KDM4E (0.47) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL9525435 | 0.82 | KDM4E (0.49) | KDM4EALDH1A1HPGDHSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0249043-B1 | QUINOLINECARBOXYLIC ACID DERIVATIVES | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-08-04 | — | — | EP | disclosed |
| US-4843070-A | BACTERIDCIDES, FUNGICIDES | NIPPON SHINYAKU CO., LTD. (JP) | 1989-06-27 | — | — | US | disclosed |
| EP-0249043-A2 | Quinolinecarboxylic acid derivatives | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1987-12-16 | — | — | EP | disclosed |