Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 10/20 | 0.56 |
| ▸ | OPRD1 | P41143 | 9/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 9/20 | 0.56 |
| ▸ | OPRL1 | P41146 | 9/20 | 0.56 |
| ▸ | DRD2 | P14416 | 2/20 | 0.51 |
| ▸ | CCR5 | P51681 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD5 | P21918 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9523741 | 0.91 | OPRM1 (0.55) | OPRM1OPRD1OPRK1OPRL1DRD2 | |
| SCHEMBL9521516 | 0.85 | SLC18A3 (0.54) | OPRM1OPRD1OPRK1OPRL1DRD2 | |
| SCHEMBL7402938 | 0.82 | OPRM1 (0.52) | OPRM1OPRD1OPRK1OPRL1DRD2 | |
| SCHEMBL21000265 | 0.81 | DRD2 (0.53) | OPRM1DRD2CCR5HRH3SLC18A3 | |
| SCHEMBL19564583 | 0.78 | DRD2 (0.53) | OPRM1DRD2CCR5SLC18A3DRD1 | |
| SCHEMBL3811836 | 0.78 | OPRM1 (0.60) | OPRM1OPRD1OPRK1OPRL1HRH3 | |
| SCHEMBL4794881 | 0.76 | OPRM1 (0.64) | OPRM1OPRD1OPRK1OPRL1HRH3 | |
| SCHEMBL13132261 | 0.76 | OPRM1 (0.64) | OPRM1OPRD1OPRK1OPRL1HRH3 | |
| SCHEMBL8734717 | 0.76 | DRD2 (0.41) | OPRM1OPRD1OPRK1OPRL1DRD2 | |
| SCHEMBL24511207 | 0.75 | DRD2 (0.49) | OPRM1DRD2DPP4SLC18A3DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0507863-A4 | SIGMA RECEPTOR LIGANDS AND THE USE THEREOF | — | 1993-07-07 | — | — | EP | claimed |
| EP-0507863-A1 | SIGMA RECEPTOR LIGANDS AND THE USE THEREOF | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 1992-10-14 | — | — | EP | claimed |
| WO-1991009594-A1 | SIGMA RECEPTOR LIGANDS AND THE USE THEREOF | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 1991-07-11 | — | — | WO | claimed |