SCHEMBL95237

SCHEMBL95237

O=[C]c1ccccc1Oc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.48
LMNA P02545 1/20 0.48
KMT2A Q03164 1/20 0.48
POLB P06746 1/20 0.47
TSHR P16473 2/20 0.46
LTA4H P09960 1/20 0.46
CTNNB1 P35222 1/20 0.46
HTT P42858 2/20 0.42
HRH1 P35367 1/20 0.41
TSPO P30536 1/20 0.41
ALDH1A1 P00352 2/20 0.40
SLC6A2 P23975 2/20 0.40
SLC6A4 P31645 2/20 0.40
RIPK1 Q13546 1/20 0.40
HPGD P15428 1/20 0.40
MAPK1 P28482 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
MAPK14 Q16539 1/20 0.40
TLR4 O00206 1/20 0.40
TLR2 O60603 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL887945 0.96 GAA (0.46) GAALMNAKMT2APOLBTSHR
SCHEMBL11337531 0.88 GAA (0.46) GAALMNAKMT2APOLBCTNNB1
SCHEMBL9166410 0.86 GAA (0.39) GAALMNAKMT2APOLBHTT
SCHEMBL10640942 0.86 PTGS2 (0.46) GAALMNAKMT2APOLBTSHR
SCHEMBL8498200 0.85 FFAR1 (0.45) GAALMNAKMT2APOLBHTT
SCHEMBL887946 0.84 GAA (0.43) GAALMNAKMT2APOLBTSHR
SCHEMBL8491438 0.84 TRPA1 (0.46) GAALMNAKMT2APOLBHTT
SCHEMBL6508125 0.81 CA4 (0.36) GAALMNAKMT2APOLBTSHR
SCHEMBL2748004 0.78 GAA (0.47) GAALMNAKMT2APOLBTSHR
SCHEMBL1162713 0.78 GAA (0.72) GAALMNAKMT2APOLBTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 221 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102471494-B star polymer Robert Bosch Ltd. (DE) 2015-11-25 CN claimed
US-9127129-B2 Star polymer ROBERT BOSCH GMBH (DE) 2015-09-08 US claimed
US-8850985-B2 Polymeric material suitable for making ammunition cartridge casings SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2014-10-07 US claimed
US-20140235784-A1 POLYMERIC MATERIAL SUITABLE FOR MAKING AMMUNITION CARTRIDGE CASINGS SOLVAY ADVANCED POLYMERS, LLC. (US) 2014-08-21 US claimed
US-20120238699-A1 STAR POLYMER ROBERT BOSCH GMBH (DE) 2012-09-20 US claimed
US-8240252-B2 Ammunition casing U.S. GOVERNMENT AS REPRESENTED BY THE SECRETARY OF THE ARMY 2012-08-14 US claimed
EP-2456812-A1 STAR POLYMER Robert Bosch GmbH (DE) 2012-05-30 EP claimed
WO-2011009949-A1 STAR POLYMER ROBERT BOSCH GMBH (DE) 2011-01-27 WO claimed
US-20100305261-A1 POLYMERICA MATERIAL SUITABLE FOR MAKING AMMUNITION CARTRIDGE CASINGS SOLVAY ADVANCED POLYMERS L.L.C. (US) 2010-12-02 US claimed
US-20100099875-A1 NEW ORTHO-FUNCTIONALIZED P-CHIRAL ARYLPHOSPHINES AND DERIVATIVES: THEIR PREPARATION AND USE IN ASYMMETRIC CATALYSIS PHOSPHOENIX SARL (FR) 2010-04-22 US claimed
US-5827927-A Macromonomers having reactive end groups MAXDEM INCORPORATED (US) 1998-10-27 US claimed
US-5824744-A RIGID POLYMER RODS AND MACROMONOMERS WITH REACTIVE END GROUPS FOR REINFORCEMENT MAXDEM INCORPORATED (US) 1998-10-20 US claimed
US-5756763-A ENZYME INHIBITOR ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYUKAI (JP) 1998-05-26 US claimed
EP-0773249-A1 Polyphenylene co-polymers MAXDEM INCORPORATED (US) 1997-05-14 EP claimed
EP-0709373-A1 NOVEL PYRROLIDINE DERIVATIVE ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1996-05-01 EP claimed
US-5403675-A Ion exchange structure having solid electrolyte of sulfonated rigid rod polyphenylene, electrodes; high proton conductivity MAXDEM, INCORPORATED (US) 1995-04-04 US claimed
WO-1994024717-A1 SULFONATED POLYMERS FOR SOLID POLYMER ELECTROLYTES MAXDEM INCORPORATED (US) 1994-10-27 WO claimed
EP-0197788-B1 PURIFICATION OF ACID HALIDES RAYCHEM CORPORATION (a Delaware corporation) (US) 1991-02-27 EP claimed
US-4314839-A 1,2,3-Thiadiazole-5-carboxylic acid amide derivatives, process for making the same and herbicidal growth regulating defoliating and fungicidal compositions containing same SCHERING AKTIENGESELLSCHAFT (DE) 1982-02-09 US claimed
US-4198205-A SULFONIC ACID-FREE DISPERSE DYES BASF AKTIENGESELLSCHAFT (DE) 1980-04-15 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100099875-A1 NEW ORTHO-FUNCTIONALIZED P-CHIRAL ARYLPHOSPHINES AND DERIVATIVES: THEIR PREPARATION AND USE IN ASYMMETRIC CATALYSIS PNP, NANP, PHOSPHO1 GAA 2354/4885LMNA 4735/4885KMT2A 2556/4885
US-20120238699-A1 STAR POLYMER STARD3, STARD10, STARD7 GAA 1935/4885LMNA 1204/4885KMT2A 2905/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.