SCHEMBL887945

SCHEMBL887945

O=[C]c1ccccc1Oc1ccccc1Oc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.46
LMNA P02545 1/20 0.46
KMT2A Q03164 1/20 0.46
POLB P06746 1/20 0.44
CTNNB1 P35222 1/20 0.43
TSHR P16473 2/20 0.42
LTA4H P09960 1/20 0.42
HTT P42858 2/20 0.42
ALDH1A1 P00352 2/20 0.42
MAPK1 P28482 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
SLC6A2 P23975 2/20 0.41
SLC6A4 P31645 2/20 0.41
HTR1A P08908 1/20 0.41
SLC6A3 Q01959 1/20 0.41
HRH1 P35367 1/20 0.39
TSPO P30536 1/20 0.39
MAPK14 Q16539 1/20 0.38
RIPK1 Q13546 1/20 0.38
HPGD P15428 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL95237 0.96 GAA (0.48) GAALMNAKMT2APOLBCTNNB1
SCHEMBL9166410 0.87 GAA (0.39) GAALMNAKMT2APOLBHTT
SCHEMBL11337531 0.85 GAA (0.46) GAALMNAKMT2APOLBCTNNB1
SCHEMBL10640942 0.82 PTGS2 (0.46) GAALMNAKMT2APOLBCTNNB1
SCHEMBL8498200 0.82 FFAR1 (0.45) GAALMNAKMT2APOLBHTT
SCHEMBL887946 0.81 GAA (0.43) GAALMNAKMT2APOLBCTNNB1
SCHEMBL8491438 0.80 TRPA1 (0.46) GAALMNAKMT2APOLBHTT
SCHEMBL9264065 0.80 LTA4H (0.65) GAALMNAKMT2ACTNNB1TSHR
SCHEMBL3893178 0.80 LTA4H (0.65) GAALMNAKMT2ACTNNB1TSHR
SCHEMBL5852017 0.80 LTA4H (0.65) GAALMNAKMT2ACTNNB1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9000084-B2 Controlled geometry composite micro pellets for use in compression molding MILLER WASTE MILLS (US) 2015-04-07 US disclosed
US-8663524-B2 Controlled geometry composite micro pellets for use in compression molding MILLER WASTE MILLS (US) 2014-03-04 US disclosed
US-20120009421-A1 CONTROLLED GEOMETRY COMPOSITE MICRO PELLETS FOR USE IN COMPRESSION MOLDING Miller Waste Mills d/b/a/ RTP Company 2012-01-12 US disclosed
US-20100291388-A1 CONTROLLED GEOMETRY COMPOSITE MICRO PELLETS FOR USE IN COMPRESSION MOLDING Miller Waste Mills d/b/a/ RTP Company 2010-11-18 US disclosed
WO-2010132066-A1 CONTROLLED GEOMETRY COMPOSITE MICRO PELLETS FOR USE IN COMPRESSION MOLDING Miller Waste Mills d/b/a RTP Company (US) 2010-11-18 WO disclosed
EP-0392008-A4 COPOLYMERS CONTAINING POLYBENZOXAZOLE, POLYBENZOTHIAZOLE AND POLYBENZIMIDAZOLE MOIETIES 1991-09-04 EP disclosed
EP-0392008-A1 COPOLYMERS CONTAINING POLYBENZOXAZOLE, POLYBENZOTHIAZOLE AND POLYBENZIMIDAZOLE MOIETIES THE DOW CHEMICAL COMPANY (US) 1990-10-17 EP disclosed
EP-0368006-A2 Copolymers containing polybenzoxazole polybenzothiazole and polybenzimidazole moieties THE DOW CHEMICAL COMPANY (US) 1990-05-16 EP disclosed
WO-1990003995-A1 COPOLYMERS CONTAINING POLYBENZOXAZOLE, POLYBENZOTHIAZOLE AND POLYBENZIMIDAZOLE MOIETIES THE DOW CHEMICAL COMPANY (US) 1990-04-19 WO disclosed