SCHEMBL887946

SCHEMBL887946

O=[C]c1cccc(Oc2ccccc2)c1Oc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.43
KMT2A Q03164 2/20 0.43
LMNA P02545 1/20 0.43
CTNNB1 P35222 1/20 0.41
TSHR P16473 2/20 0.40
ALDH1A1 P00352 2/20 0.40
HPGD P15428 1/20 0.40
LTA4H P09960 1/20 0.39
DPP4 P27487 1/20 0.39
POLB P06746 1/20 0.39
HTT P42858 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.37
HRH1 P35367 1/20 0.37
TSPO P30536 1/20 0.37
KDM4E B2RXH2 1/20 0.36
GLA P06280 1/20 0.36
MAPT P10636 1/20 0.36
SLC6A2 P23975 2/20 0.36
SLC6A4 P31645 2/20 0.36
RIPK1 Q13546 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL95237 0.84 GAA (0.48) GAAKMT2ALMNACTNNB1TSHR
SCHEMBL10631594 0.81 MAOB (0.41) GAAKMT2ATSHRALDH1A1HPGD
SCHEMBL7886724 0.81 ALDH1A1 (0.40) GAAKMT2ALMNACTNNB1TSHR
SCHEMBL887945 0.81 GAA (0.46) GAAKMT2ALMNACTNNB1TSHR
SCHEMBL9780873 0.80 LTA4H (0.55) GAAKMT2ALMNACTNNB1TSHR
SCHEMBL10640942 0.79 PTGS2 (0.46) GAAKMT2ALMNACTNNB1TSHR
SCHEMBL9273369 0.78 TSHR (0.52) GAAKMT2ALMNACTNNB1TSHR
SCHEMBL9275082 0.76 TSHR (0.50) GAAKMT2ALMNACTNNB1TSHR
SCHEMBL11816942 0.76 LTA4H (0.57) GAAKMT2ALMNACTNNB1TSHR
SCHEMBL28416915 0.76 TSHR (0.50) GAAKMT2ALMNACTNNB1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9000084-B2 Controlled geometry composite micro pellets for use in compression molding MILLER WASTE MILLS (US) 2015-04-07 US disclosed
US-8663524-B2 Controlled geometry composite micro pellets for use in compression molding MILLER WASTE MILLS (US) 2014-03-04 US disclosed
US-20120009421-A1 CONTROLLED GEOMETRY COMPOSITE MICRO PELLETS FOR USE IN COMPRESSION MOLDING Miller Waste Mills d/b/a/ RTP Company 2012-01-12 US disclosed
US-20100291388-A1 CONTROLLED GEOMETRY COMPOSITE MICRO PELLETS FOR USE IN COMPRESSION MOLDING Miller Waste Mills d/b/a/ RTP Company 2010-11-18 US disclosed
WO-2010132066-A1 CONTROLLED GEOMETRY COMPOSITE MICRO PELLETS FOR USE IN COMPRESSION MOLDING Miller Waste Mills d/b/a RTP Company (US) 2010-11-18 WO disclosed
EP-0392008-A4 COPOLYMERS CONTAINING POLYBENZOXAZOLE, POLYBENZOTHIAZOLE AND POLYBENZIMIDAZOLE MOIETIES 1991-09-04 EP disclosed
EP-0392008-A1 COPOLYMERS CONTAINING POLYBENZOXAZOLE, POLYBENZOTHIAZOLE AND POLYBENZIMIDAZOLE MOIETIES THE DOW CHEMICAL COMPANY (US) 1990-10-17 EP disclosed
EP-0368006-A2 Copolymers containing polybenzoxazole polybenzothiazole and polybenzimidazole moieties THE DOW CHEMICAL COMPANY (US) 1990-05-16 EP disclosed
WO-1990003995-A1 COPOLYMERS CONTAINING POLYBENZOXAZOLE, POLYBENZOTHIAZOLE AND POLYBENZIMIDAZOLE MOIETIES THE DOW CHEMICAL COMPANY (US) 1990-04-19 WO disclosed