Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | CASP3 | P42574 | 1/20 | 0.57 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.57 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.57 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.57 |
| ▸ | MGLL | Q99685 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9526019 | 0.89 | RAB9A (0.56) | RAB9ANPC1MGLLMAPTLMNA | |
| SCHEMBL9525190 | 0.85 | MEN1 (0.55) | RAB9ANPC1MGLLMAPTLMNA | |
| SCHEMBL31525882 | 0.83 | NPC1 (0.58) | RAB9ANPC1CASP3MGLLMAPT | |
| SCHEMBL4372681 | 0.83 | NPC1 (0.60) | RAB9ANPC1CASP3MGLLMAPT | |
| SCHEMBL17761732 | 0.82 | ALDH1A1 (0.60) | RAB9ANPC1CYP2C9CYP2C19MAPK1 | |
| SCHEMBL11766069 | 0.82 | NPC1 (0.72) | RAB9ANPC1MAPK1MGLLMAPT | |
| SCHEMBL3175561 | 0.82 | MGLL (0.60) | RAB9ANPC1MGLLMAPTPOLB | |
| SCHEMBL14209030 | 0.81 | POLB (0.60) | RAB9ANPC1CYP2C9CYP2C19MAPK1 | |
| SCHEMBL7256722 | 0.80 | CYP1A2 (0.58) | RAB9ANPC1CYP2C9CYP2C19MAPK1 | |
| SCHEMBL3038608 | 0.80 | MGLL (0.58) | RAB9ANPC1MGLLMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366542-B1 | 5-SUBSTITUTED ORTHO-AMINOPHENOLS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE OXIDATION DYEING OF KERATINIC FIBRES | L'OREAL (FR) | 1993-07-14 | — | — | EP | disclosed |
| US-5145483-A | Hair dyes | L'OREAL (FR) | 1992-09-08 | — | — | US | disclosed |
| EP-0366542-A1 | 5-Substituted ortho-aminophenols, process for their preparation and their use in the oxidation dyeing of keratinic fibres | L'OREAL (FR) | 1990-05-02 | — | — | EP | disclosed |