Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | MGLL | Q99685 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | F10 | P00742 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9523995 | 0.89 | RAB9A (0.58) | RAB9ANPC1MGLLTP53MAPT | |
| SCHEMBL9525190 | 0.86 | MEN1 (0.55) | RAB9ANPC1MGLLTP53MAPT | |
| SCHEMBL4372681 | 0.84 | NPC1 (0.60) | RAB9ANPC1MGLLTP53MAPT | |
| SCHEMBL31525882 | 0.82 | NPC1 (0.58) | RAB9ANPC1MGLLMAPTSMN1; SMN2 | |
| SCHEMBL9527633 | 0.81 | RAB9A (0.50) | RAB9AMAPTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL9527627 | 0.81 | RAB9A (0.50) | RAB9ANPC1MGLLMAPTALDH1A1 | |
| SCHEMBL13529179 | 0.80 | CASP3 (0.56) | RAB9ANPC1MGLLTP53MAPT | |
| SCHEMBL9524957 | 0.80 | F10 (0.56) | RAB9ANPC1MGLLTP53MAPT | |
| SCHEMBL16193532 | 0.79 | NPC1 (0.69) | RAB9ANPC1MGLLTP53MAPT | |
| SCHEMBL30522295 | 0.79 | NPC1 (0.69) | RAB9ANPC1MGLLTP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366542-B1 | 5-SUBSTITUTED ORTHO-AMINOPHENOLS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE OXIDATION DYEING OF KERATINIC FIBRES | L'OREAL (FR) | 1993-07-14 | — | — | EP | disclosed |
| US-5145483-A | Hair dyes | L'OREAL (FR) | 1992-09-08 | — | — | US | disclosed |
| EP-0366542-A1 | 5-Substituted ortho-aminophenols, process for their preparation and their use in the oxidation dyeing of keratinic fibres | L'OREAL (FR) | 1990-05-02 | — | — | EP | disclosed |