Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.37 |
| ▸ | ICMT | O60725 | 1/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9527775 | 0.95 | CYP1A2 (0.47) | CYP1A2GAAHPGDTSHRCSNK2A2 | |
| SCHEMBL9525025 | 0.89 | ALDH1A1 (0.44) | — | |
| SCHEMBL9525627 | 0.84 | LCK (0.40) | — | |
| SCHEMBL9525682 | 0.76 | NAAA (0.52) | GAAHPGDTSHR | |
| SCHEMBL9525892 | 0.76 | NAAA (0.52) | GAAHPGDTSHR | |
| SCHEMBL9524674 | 0.73 | KMT2A (0.45) | HPGD | |
| SCHEMBL9527401 | 0.73 | TSHR (0.51) | HPGDTSHR | |
| SCHEMBL9524895 | 0.73 | ALDH1A1 (0.47) | HPGDTSHR | |
| SCHEMBL3094124 | 0.71 | ADORA3 (0.48) | CYP1A2GAAHPGDTSHRHSP90AA1 | |
| SCHEMBL5178440 | 0.70 | HDAC6 (0.57) | GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277791-B1 | CINNOLINE-CARBOXAMIDES AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA S.r.l. (IT) | 1993-06-02 | — | — | EP | disclosed |
| US-4826837-A | IMMUNOMODULATORS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1989-05-02 | — | — | US | disclosed |
| EP-0277791-A2 | Cinnoline-carboxamides and process for their preparation | FARMITALIA CARLO ERBA S.r.l. (IT) | 1988-08-10 | — | — | EP | disclosed |