Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | BRD4 | O60885 | 1/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | MB | P02144 | 1/20 | 0.52 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.52 |
| ▸ | CA3 | P07451 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | RARG | P13631 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9627355 | 0.98 | HTT (0.58) | HTTPKMSMN1; SMN2MAPTPOLB | |
| SCHEMBL4958020 | 0.89 | MAPT (0.69) | HTTPKMSMN1; SMN2MAPTPOLB | |
| SCHEMBL3192352 | 0.80 | PKM (0.65) | HTTPKMSMN1; SMN2MAPTPOLB | |
| SCHEMBL2195425 | 0.80 | IDO1 (0.48) | HTTMAPTPOLBNPC1RAB9A | |
| SCHEMBL6807072 | 0.80 | PKM (0.51) | PKMSMN1; SMN2MAPTPOLBNPC1 | |
| SCHEMBL9523963 | 0.78 | POLB (0.51) | HTTPKMSMN1; SMN2MAPTPOLB | |
| SCHEMBL6941725 | 0.78 | RAB9A (0.51) | HTTPKMSMN1; SMN2MAPTPOLB | |
| SCHEMBL23033341 | 0.77 | HTT (0.55) | HTTPKMSMN1; SMN2MAPTPOLB | |
| Hydrochloric Acid SCHEMBL9626583 | 0.77 | POLB (0.50) | HTTPKMSMN1; SMN2MAPTPOLB | |
| SCHEMBL11417747 | 0.77 | SMN1; SMN2 (0.59) | HTTPKMSMN1; SMN2MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366542-B1 | 5-SUBSTITUTED ORTHO-AMINOPHENOLS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE OXIDATION DYEING OF KERATINIC FIBRES | L'OREAL (FR) | 1993-07-14 | — | — | EP | claimed |
| EP-0366542-A1 | 5-Substituted ortho-aminophenols, process for their preparation and their use in the oxidation dyeing of keratinic fibres | L'OREAL (FR) | 1990-05-02 | — | — | EP | claimed |
| US-5145483-A | Hair dyes | L'OREAL (FR) | 1992-09-08 | — | — | US | disclosed |
| EP-0366542-A1 | 5-Substituted ortho-aminophenols, process for their preparation and their use in the oxidation dyeing of keratinic fibres | L'OREAL (FR) | 1990-05-02 | — | — | EP | disclosed |