Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 8/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MC4R | P32245 | 1/20 | 0.44 |
| ▸ | SCN4A | P35499 | 1/20 | 0.44 |
| ▸ | MC3R | P41968 | 1/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9522516 | 0.82 | KCNK3 (0.59) | MAPTALDH1A1KDM4EHPGDALOX15 | |
| SCHEMBL8000882 | 0.80 | TRPV1 (0.66) | TRPV1MAPTALDH1A1KDM4EHSD17B10 | |
| SCHEMBL14095548 | 0.77 | HDAC6 (0.57) | TRPV1 | |
| SCHEMBL2307872 | 0.76 | S1PR4 (0.56) | MAPTALDH1A1KDM4EHPGDALOX15 | |
| SCHEMBL9523014 | 0.75 | S1PR4 (0.69) | TRPV1MAPTALDH1A1KDM4EHPGD | |
| SCHEMBL12652061 | 0.74 | MAPT (0.59) | MAPTALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL9522743 | 0.74 | S1PR4 (0.58) | MAPTALDH1A1KDM4EHPGDS1PR4 | |
| SCHEMBL9522611 | 0.74 | S1PR4 (0.51) | MAPTALDH1A1KDM4EHPGDALOX15 | |
| SCHEMBL4138460 | 0.73 | POLB (0.67) | MAPTKDM4EHPGDS1PR4LMNA | |
| SCHEMBL10357153 | 0.72 | POLB (0.63) | MAPTALDH1A1HPGDS1PR4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0279633-B1 | ANTICONVULSANT AGENTS | ELI LILLY AND COMPANY (US) | 1993-04-07 | — | — | EP | disclosed |
| US-4981866-A | BENZAMIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 1991-01-01 | — | — | US | disclosed |
| US-4939163-A | 4-substituted benzamide derivatives | ELI LILLY AND COMPANY (US) | 1990-07-03 | — | — | US | disclosed |
| US-4835181-A | Anticonvulsant agents using cyano dimethylphenyl benzamides | ELI LILLY AND COMPANY (US) | 1989-05-30 | — | — | US | disclosed |
| EP-0279633-A2 | Anticonvulsant agents | ELI LILLY AND COMPANY (US) | 1988-08-24 | — | — | EP | disclosed |