Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.37 |
| ▸ | TYMP | P19971 | 2/20 | 0.36 |
| ▸ | AHR | P35869 | 3/20 | 0.34 |
| ▸ | KMO | O15229 | 1/20 | 0.34 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9701671 | 0.83 | BRD4 (0.42) | NOTUMHTTKDM4EGAANPY5R | |
| SCHEMBL9702588 | 0.81 | ALPL (0.32) | MAPTAHR | |
| SCHEMBL9251638 | 0.81 | PTGER3 (0.46) | — | |
| SCHEMBL9525928 | 0.79 | CYP11B1 (0.33) | MEN1KMT2AMAPT | |
| SCHEMBL9528858 | 0.79 | TNKS (0.44) | KDM4EPKM | |
| SCHEMBL9700393 | 0.78 | — | — | |
| SCHEMBL9700756 | 0.78 | SNCA (0.37) | MEN1HTTKMT2AKDM4EGAA | |
| SCHEMBL9754463 | 0.78 | PTGER3 (0.39) | — | |
| SCHEMBL703287 | 0.76 | AHR (0.48) | NOTUMMEN1HTTKMT2AKDM4E | |
| SCHEMBL9700663 | 0.76 | MAPT (0.36) | NOTUMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550576-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-07-14 | — | — | EP | claimed |
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | claimed |
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |