Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 4/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9700756 | 0.85 | SNCA (0.37) | KDM4EALDH1A1LMNAGLAGAA | |
| SCHEMBL9525656 | 0.83 | NOTUM (0.40) | NOTUMKDM4EGAAHTTNPY5R | |
| SCHEMBL9700666 | 0.81 | ALDH1A1 (0.53) | NOTUMKDM4EALDH1A1LMNAGLA | |
| SCHEMBL9700407 | 0.81 | IDO1 (0.41) | NOTUMKDM4EALDH1A1LMNAGLA | |
| SCHEMBL9700701 | 0.81 | NOTUM (0.41) | NOTUMKDM4EALDH1A1LMNAGLA | |
| SCHEMBL9700679 | 0.81 | MAOA (0.37) | NOTUMKDM4E | |
| SCHEMBL9251638 | 0.80 | PTGER3 (0.46) | — | |
| SCHEMBL9528770 | 0.79 | KDM4E (0.48) | BRD4NOTUMKDM4EALDH1A1LMNA | |
| SCHEMBL9700393 | 0.77 | — | — | |
| SCHEMBL9526113 | 0.77 | MAPT (0.41) | KDM4EALDH1A1LMNAGLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | claimed |
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |