Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 18/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9251638 | 0.89 | PTGER3 (0.46) | PTGER3PIM1 | |
| SCHEMBL9754365 | 0.84 | ALDH1A1 (0.36) | — | |
| SCHEMBL9535284 | 0.83 | KDM4E (0.41) | PIM1 | |
| SCHEMBL9525656 | 0.78 | NOTUM (0.40) | — | |
| SCHEMBL9701671 | 0.77 | BRD4 (0.42) | — | |
| SCHEMBL9700756 | 0.77 | SNCA (0.37) | — | |
| SCHEMBL9754436 | 0.76 | ALDH1A1 (0.33) | — | |
| SCHEMBL9754374 | 0.76 | NPC1 (0.40) | — | |
| SCHEMBL9700679 | 0.75 | MAOA (0.37) | — | |
| SCHEMBL9525928 | 0.75 | CYP11B1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991017987-A1 | PHENOL AND PYRIDINOL DERIVATIVES AS PHARMACEUTICALS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1991-11-28 | — | — | WO | claimed |
| WO-1991017987-A1 | PHENOL AND PYRIDINOL DERIVATIVES AS PHARMACEUTICALS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1991-11-28 | — | — | WO | disclosed |