Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 2/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
| ▸ | AHR | P35869 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5809202 | 0.82 | AHR (0.39) | ALPLCES1AHR | |
| SCHEMBL9525656 | 0.81 | NOTUM (0.40) | AHRMAPT | |
| SCHEMBL9701671 | 0.75 | BRD4 (0.42) | ALDH1A1 | |
| SCHEMBL9535284 | 0.73 | KDM4E (0.41) | ALPL | |
| SCHEMBL9700393 | 0.72 | — | — | |
| SCHEMBL9754365 | 0.72 | ALDH1A1 (0.36) | ALDH1A1MAPT | |
| SCHEMBL9754399 | 0.70 | MAOB (0.36) | ALDH1A1MAPT | |
| SCHEMBL9754396 | 0.70 | ACVR1 (0.42) | ALDH1A1MAPT | |
| SCHEMBL9251638 | 0.69 | PTGER3 (0.46) | — | |
| SCHEMBL9700756 | 0.69 | SNCA (0.37) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | claimed |
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |