Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCOA1 | Q15788 | 1/20 | 0.44 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.44 |
| ▸ | TPMT | P51580 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7670073 | 0.76 | TPMT (0.65) | NCOA1NCOA3TPMTSMN1; SMN2TSHR | |
| SCHEMBL1134614 | 0.75 | TSHR (0.72) | NCOA1NCOA3TPMTSMN1; SMN2MAPT | |
| SCHEMBL10601596 | 0.73 | PPARG (0.63) | ALDH1A1PPARGPPARAMEN1KMT2A | |
| SCHEMBL31063218 | 0.73 | TPMT (0.49) | NCOA1NCOA3TPMTMAPTRAB9A | |
| SCHEMBL6343700 | 0.71 | ALDH1A1 (0.65) | MAPTL3MBTL1HTTALDH1A1MEN1 | |
| SCHEMBL24488953 | 0.71 | CREBBP (0.44) | NCOA1NCOA3SMN1; SMN2L3MBTL1TSHR | |
| SCHEMBL3546860 | 0.70 | TPMT (0.58) | TPMTL3MBTL1TSHRHTTALDH1A1 | |
| SCHEMBL13807390 | 0.70 | NOTUM (0.49) | NCOA1NCOA3TPMTSMN1; SMN2MAPT | |
| Butane SCHEMBL3738130 | 0.69 | LMNA (0.60) | TPMTMAPTALDH1A1LMNAMEN1 | |
| SCHEMBL26810030 | 0.69 | TPMT (0.51) | NCOA1NCOA3TPMTSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550576-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-07-14 | — | — | EP | disclosed |
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |