Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9524781 | 0.84 | NPC1 (0.38) | TSHRNPSR1POLBTAS1R3TAS1R1 | |
| SCHEMBL9528461 | 0.83 | NPC1 (0.37) | TSHRNPSR1POLBTAS1R3TAS1R1 | |
| Hydrochloric Acid SCHEMBL9528597 | 0.81 | TSHR (0.39) | TSHRNPSR1SMN1; SMN2SLC6A2SLC6A4 | |
| SCHEMBL9525174 | 0.81 | NPC1 (0.38) | TSHRNPSR1POLBTAS1R3TAS1R1 | |
| SCHEMBL9528525 | 0.80 | POLB (0.34) | TSHRNPSR1POLBTAS1R3TAS1R1 | |
| SCHEMBL9525693 | 0.78 | POLB (0.35) | TSHRNPSR1POLBTAS1R3TAS1R1 | |
| SCHEMBL9526317 | 0.77 | POLB (0.35) | TSHRNPSR1POLBTAS1R3TAS1R1 | |
| SCHEMBL9524919 | 0.77 | HTT (0.51) | TSHRPOLBHTTSMN1; SMN2ALOX15 | |
| SCHEMBL9524060 | 0.74 | OPRM1 (0.37) | TSHRNPSR1HTTSMN1; SMN2SLC6A2 | |
| SCHEMBL9525136 | 0.74 | OPRM1 (0.37) | TSHRNPSR1SMN1; SMN2SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301751-B1 | PYRIDINIUM DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1993-03-10 | — | — | EP | disclosed |
| US-4962113-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD (JP) | 1990-10-09 | — | — | US | disclosed |
| EP-0301751-A1 | Pyridinium derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1989-02-01 | — | — | EP | disclosed |