Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 5/20 | 0.60 |
| ▸ | ITGB7 | P26010 | 5/20 | 0.60 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.48 |
| ▸ | CXCR1 | P25024 | 3/20 | 0.48 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.48 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | CTSV | O60911 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9526381 | 0.84 | ITGA4 (0.43) | ITGA4ITGB7TDP1 | |
| SCHEMBL10429974 | 0.81 | TDP1 (0.48) | ITGA4ITGB7KMT2ATDP1LMNA | |
| SCHEMBL11092184 | 0.80 | ITGA4 (0.51) | ITGA4ITGB7KMT2AMAPT | |
| SCHEMBL9524996 | 0.80 | CXCR1 (0.60) | ITGA4ITGB7CYP19A1CXCR1CXCR2 | |
| SCHEMBL9525716 | 0.80 | ITGA4 (0.54) | ITGA4ITGB7CYP19A1CXCR1CXCR2 | |
| SCHEMBL9527627 | 0.78 | RAB9A (0.50) | CYP19A1MEN1KMT2AMAPTGAA | |
| SCHEMBL19511793 | 0.73 | TDP1 (0.60) | ITGA4ITGB7CYP19A1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL27489676 | 0.72 | ITGA4 (0.61) | ITGA4ITGB7MEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL27489675 | 0.72 | ITGA4 (0.61) | ITGA4ITGB7MEN1KMT2AMAPT | |
| SCHEMBL3584166 | 0.72 | CRHBP (0.51) | KMT2AMAPTGAATDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366542-B1 | 5-SUBSTITUTED ORTHO-AMINOPHENOLS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE OXIDATION DYEING OF KERATINIC FIBRES | L'OREAL (FR) | 1993-07-14 | — | — | EP | disclosed |
| EP-0366542-A1 | 5-Substituted ortho-aminophenols, process for their preparation and their use in the oxidation dyeing of keratinic fibres | L'OREAL (FR) | 1990-05-02 | — | — | EP | disclosed |