Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 1/20 | 0.43 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | MBTPS1 | Q14703 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | PLAT | P00750 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10429974 | 0.84 | TDP1 (0.48) | ITGA4ITGB7TACR1TYRCA12 | |
| SCHEMBL9525707 | 0.84 | ITGA4 (0.60) | ITGA4ITGB7TDP1 | |
| SCHEMBL9527627 | 0.81 | RAB9A (0.50) | TACR1 | |
| SCHEMBL9524957 | 0.78 | F10 (0.56) | POLBCA12CA1CA2CA9 | |
| SCHEMBL9526385 | 0.78 | LMNA (0.40) | ITGA4ITGB7TACR1CA12CA1 | |
| SCHEMBL31195801 | 0.72 | ALDH1A1 (0.55) | TACR1TDP1ACEMBTPS1 | |
| SCHEMBL8351818 | 0.71 | ALDH1A1 (0.53) | TACR1POLBTDP1ACE | |
| SCHEMBL8348342 | 0.71 | ALDH1A1 (0.53) | TACR1POLBTDP1ACE | |
| SCHEMBL3783672 | 0.71 | MGLL (0.54) | POLBCA12CA1CA2CA9 | |
| SCHEMBL10660589 | 0.71 | ALDH1A1 (0.51) | TACR1POLBACEMBTPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366542-B1 | 5-SUBSTITUTED ORTHO-AMINOPHENOLS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE OXIDATION DYEING OF KERATINIC FIBRES | L'OREAL (FR) | 1993-07-14 | — | — | EP | disclosed |
| EP-0366542-A1 | 5-Substituted ortho-aminophenols, process for their preparation and their use in the oxidation dyeing of keratinic fibres | L'OREAL (FR) | 1990-05-02 | — | — | EP | disclosed |